SCHEMBL10355459

SCHEMBL10355459

c1snnc1N=Nc1csnn1

nearest known ligand 0.33

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 2/20 0.33
MEN1 O00255 1/20 0.33
NPC1 O15118 1/20 0.33
RAB9A P51151 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
POLB P06746 1/20 0.33
NOTUM Q6P988 1/20 0.33
LMNA P02545 1/20 0.31
ALDH1A1 P00352 1/20 0.30
ATM Q13315 1/20 0.30
L3MBTL1 Q9Y468 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL183486 0.78
SCHEMBL11168114 0.72
SCHEMBL9657528 0.72
SCHEMBL10481425 0.72 TSHR (0.48) KMT2AMEN1NPC1RAB9ASMN1; SMN2
SCHEMBL9840014 0.61
SCHEMBL156583 0.61
SCHEMBL213293 0.61
SCHEMBL125479 0.61
SCHEMBL11436591 0.61
SCHEMBL18980923 0.57

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0210139-B1 CATIONIC AZO-1,2,3-THIADIAZOLE COMPOUNDS CIBA-GEIGY AG (CH) 1990-09-19 EP claimed
EP-0210139-B1 CATIONIC AZO-1,2,3-THIADIAZOLE COMPOUNDS CIBA-GEIGY AG (CH) 1990-09-19 EP disclosed
EP-0210139-A2 Cationic azo-1,2,3-thiadiazole compounds CIBA-GEIGY AG (CH) 1987-01-28 EP disclosed