⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9840014 | 0.63 | — | — | |
| SCHEMBL7338033 | 0.63 | — | — | |
| SCHEMBL11436591 | 0.62 | — | — | |
| SCHEMBL1393445 | 0.62 | — | — | |
| SCHEMBL125479 | 0.62 | — | — | |
| SCHEMBL156583 | 0.62 | — | — | |
| SCHEMBL10355459 | 0.61 | KMT2A (0.33) | — | |
| SCHEMBL289428 | 0.57 | — | — | |
| SCHEMBL3508035 | 0.57 | MAPT (0.34) | — | |
| SCHEMBL194886 | 0.57 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1257 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111868055-B | Inhibitors of TRPC6 | 勃林格殷格翰国际有限公司 | 2024-03-08 | — | — | CN | claimed |
| US-20230372309-A1 | ALPHA-2 ADRENERGIC RECEPTOR ANTAGONIST | KYOTO UNIVERSITY (JP) | 2023-11-23 | — | — | US | claimed |
| EP-4218818-A1 | ALPHA-2 ADRENERGIC RECEPTOR ANTAGONIST | Kyoto University (JP) | 2023-08-02 | — | — | EP | claimed |
| CN-116234578-A | Alpha 2 adrenoreceptor antagonists | 国立大学法人京都大学 | 2023-06-06 | — | — | CN | claimed |
| CN-111868055-A | Inhibitors of TRPC6 | 勃林格殷格翰国际有限公司 | 2020-10-30 | — | — | CN | claimed |
| EP-2430006-B1 | CYCLOPENTA[C]PYRROLE-2-CARBOXYLATE DERIVATIVES, PREPARATION THEREOF, AND THERAPEUTIC USE THEREOF | SANOFI SA (FR) | 2014-11-26 | — | — | EP | claimed |
| US-8697883-B2 | Cyclopenta[C]pyrrole-2-carboxylate derivatives, preparation thereof and therapeutic use thereof | SANOFI (FR) | 2014-04-15 | — | — | US | claimed |
| CN-102816134-A | 1,2,3-thiadiazole-containing sulfilimine (sulfonimine) compounds and their preparation method and use | UNIV NANKAI | 2012-12-12 | — | — | CN | claimed |
| US-20120214851-A1 | Aminobenzamide Derivatives as Useful Agents for Controlling Animal Parasites | BAYER CROPSCIENCE AG (DE) | 2012-08-23 | — | — | US | claimed |
| EP-2484688-A1 | PEPTIDE EPOXYKETONES FOR PROTEASOME INHIBITION | Onyx Therapeutics, Inc. (US) | 2012-08-08 | — | — | EP | claimed |
| WO-1999012892-A1 | SUBSTITUTED ALKENOIC ACIDS AND THEIR DERIVATIVES | BAYER AKTIENGESELLSCHAFT (DE) | 1999-03-18 | — | — | WO | claimed |
| CN-1197455-A | Substituted phenyluracils | BAYER AG (DE) | 1998-10-28 | — | — | CN | claimed |
| EP-0843667-A1 | SUBSTITUTED PHENYLURACILS | BAYER AG (DE) | 1998-05-27 | — | — | EP | claimed |
| US-5686392-A | Process for preparing substituted N-carbamoyl-Tetrazolinones | BAYER AKTIENGESELLSCHAFT (DE) | 1997-11-11 | — | — | US | claimed |
| WO-1997005118-A1 | SUBSTITUTED PHENYLURACILS | BAYER AKTIENGESELLSCHAFT (DE) | 1997-02-13 | — | — | WO | claimed |
| EP-0726259-A1 | Process for the preparation of substituted N-carbamoyl-tetrazolinones | BAYER AG (DE) | 1996-08-14 | — | — | EP | claimed |
| US-5439904-A | Enzyme inhibitors of human leukocyte elastase; respiratory system disorders; antiarthritic agents | SYNPHAR LABORATORIES, INC. (CA) | 1995-08-08 | — | — | US | claimed |
| US-5240924-A | Dipeptide hypotensives | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1993-08-31 | — | — | US | claimed |
| EP-0467183-A1 | Herbicides based on sulfonylated (thio)carbamic acid esters, sulfonylated carbamic acid esters and process for their preparation | BAYER AG (DE) | 1992-01-22 | — | — | EP | claimed |
| EP-0201459-A1 | Acylaminomethyl-penem compounds, their preparation and pharmaceutical formulations containing them | CIBA-GEIGY AG (CH) | 1986-11-12 | — | — | EP | claimed |