Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | GAA | P10253 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 5/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.40 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.38 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.33 |
| ▸ | NQO1 | P15559 | 1/20 | 0.33 |
| ▸ | SGPL1 | O95470 | 1/20 | 0.33 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10355463 | 1.00 | MAPT (0.40) | MAPTGAAMEN1KMT2ARAB9A | |
| SCHEMBL10875327 | 0.92 | NR5A1 (0.41) | MAPTGAAMEN1KMT2ARAB9A | |
| SCHEMBL10459673 | 0.90 | DGAT1 (0.44) | MAPTGAARAB9ANPC1CYP1A2 | |
| SCHEMBL10459674 | 0.90 | DGAT1 (0.44) | MAPTGAARAB9ANPC1CYP1A2 | |
| SCHEMBL10460797 | 0.90 | DGAT1 (0.44) | MAPTGAARAB9ANPC1CYP1A2 | |
| SCHEMBL10460798 | 0.90 | DGAT1 (0.44) | MAPTGAARAB9ANPC1CYP1A2 | |
| SCHEMBL10461846 | 0.89 | DGAT1 (0.44) | MAPTGAAMEN1KMT2ARAB9A | |
| SCHEMBL10461844 | 0.89 | DGAT1 (0.44) | MAPTGAAMEN1KMT2ARAB9A | |
| SCHEMBL10715995 | 0.85 | KDM4E (0.41) | MAPTGAARAB9ANPC1CYP1A2 | |
| SCHEMBL10715202 | 0.85 | DGAT1 (0.42) | MAPTGAARAB9ANPC1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0194153-B1 | PYRIDINE DERIVATIVES | Chisso Corporation (JP) | 1990-10-31 | — | — | EP | disclosed |
| US-4684477-A | LOW VISCOSITY, LOW VOLTAGE | CHISSO CORPORATION (JP) | 1987-08-04 | — | — | US | disclosed |
| EP-0194153-A2 | Pyridine derivatives | Chisso Corporation (JP) | 1986-09-10 | — | — | EP | disclosed |