SCHEMBL10355486

SCHEMBL10355486

CO[Si](O[SiH](C)C)(c1ccccc1)c1ccccc1

nearest known ligand 0.32

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
CA4 P22748 1/20 0.32
ESR1 P03372 1/20 0.30
ESR2 Q92731 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL330426 0.89 ESR1 (0.33) CA4ESR1ESR2
SCHEMBL20492835 0.86 ESR1 (0.32) ESR1ESR2
SCHEMBL2600706 0.84 ESR1 (0.31) ESR1ESR2
SCHEMBL15912069 0.83 CA4 (0.30) CA4
SCHEMBL18143561 0.83 ESR1 (0.30) ESR1ESR2
SCHEMBL17807947 0.82
SCHEMBL12023368 0.81
SCHEMBL10294617 0.81
SCHEMBL49008 0.81 CA4 (0.41) CA4ESR1ESR2
SCHEMBL27596877 0.81 CA4 (0.41) CA4ESR1ESR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8431953-B2 Silicone resin composition and an optical semiconductor device making use of the composition SHIN-ETSU CHEMICAL CO., LTD. (JP) 2013-04-30 US disclosed
US-20120184663-A1 SILICONE RESIN COMPOSITION AND AN OPTICAL SEMICONDUCTOR DEVICE MAKING USE OF THE COMPOSITION SHIN-ETSU CHEMICAL CO., LTD. (JP) 2012-07-19 US disclosed