SCHEMBL49008

SCHEMBL49008

CO[Si](OC)(c1ccccc1)c1ccccc1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA4 P22748 2/20 0.41
ESR1 P03372 1/20 0.37
ESR2 Q92731 1/20 0.37
CA12 O43570 1/20 0.36
CA1 P00915 1/20 0.36
CA2 P00918 1/20 0.36
CA7 P43166 1/20 0.36
CA9 Q16790 1/20 0.36
CA14 Q9ULX7 1/20 0.36
POLB P06746 2/20 0.36
ALDH1A1 P00352 3/20 0.35
LTA4H P09960 3/20 0.35
CYP1A2 P05177 1/20 0.35
CYP2C19 P33261 1/20 0.35
TSHR P16473 4/20 0.33
SMN1; SMN2 Q16637 2/20 0.33
MAPK1 P28482 2/20 0.33
LMNA P02545 1/20 0.33
ALOX12 P18054 1/20 0.33
ACHE P22303 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27596877 1.00 CA4 (0.41) CA4ESR1ESR2CA12CA1
SCHEMBL27743669 0.97 CA4 (0.39) CA4ESR1ESR2CA12CA1
SCHEMBL11588483 0.97 CA1 (0.41) CA4ESR1ESR2CA12CA1
SCHEMBL706592 0.97 ESR1 (0.41) CA4ESR1ESR2CA12CA1
SCHEMBL28085512 0.92 ESR1 (0.38) CA4ESR1ESR2CA12CA1
Biphenyl SCHEMBL28211836 0.92 ALDH1A1 (0.45) CA4POLBALDH1A1CYP1A2TSHR
SCHEMBL6861206 0.90 ESR1 (0.37) CA4ESR1ESR2CA12CA1
SCHEMBL7745568 0.90 POLB (0.35) CA4ESR1ESR2CA12CA1
SCHEMBL5419766 0.90 ESR1 (0.37) CA4ESR1ESR2CA12CA1
SCHEMBL27346093 0.90 ESR1 (0.37) CA4ESR1ESR2CA12CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 28221 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115974908-B Organic silicon boron flame retardant and preparation method and application thereof JIANG University OF TECHNOLOGY (CN) 2026-05-26 CN claimed
CN-122080275-A Polypropylene and preparation method and application thereof 2026-05-26 CN claimed
CN-122080612-A Acrylic acid in-situ polymerized silane modified polyether hybrid resin, application, waterproof coating and preparation method 2026-05-26 CN claimed
CN-116144183-B High-temperature vulcanized silicone rubber and preparation method thereof SHANDONG UNIVERSITY (CN) 2026-05-26 CN claimed
CN-122091713-A Sulfide electrolyte with shell-core structure, preparation method thereof and solid-state battery 2026-05-26 CN claimed
CN-122060407-A Fluorine-free super-hydrophobic high-temperature-resistant coating material and preparation method and application thereof 江南大学 2026-05-19 CN claimed
CN-122060146-A Yellowing-resistant epoxy resin curing agent and preparation method and application thereof 广东电网有限责任公司电力科学研究院 2026-05-19 CN claimed
CN-116854848-B Preparation method of ultra-high molecular weight poly alpha-olefin 金浦新材料股份有限公司 2026-05-19 CN claimed
CN-122037004-A Catalyst component for olefin polymerization, catalyst, application of catalyst and olefin polymerization method 中国石油化工股份有限公司 2026-05-15 CN claimed
CN-122037014-A Catalyst component for olefin polymerization, catalyst and application thereof, and olefin polymerization method 中国石油化工股份有限公司 2026-05-15 CN claimed
EP-0061871-B1 PRIMER COMPOSITION USED FOR ADHESION OF SILICONE RUBBER AND APPLICATION METHOD Toray Silicone Company Limited (JP) 1984-10-31 EP claimed
US-4401500-A SILICONE RUBBERS, ALKOXYSILANE, HYDROPEROXIDE DOW CORNING CORPORATION (US) 1983-08-30 US claimed
EP-0061871-A1 Primer composition used for adhesion of silicone rubber and application method Toray Silicone Company Limited (JP) 1982-10-06 EP claimed
US-4322513-A Epoxy resin-based compositions TOKYO SHIBAURA DENKI KABUSHIKI KAISHA (JP) 1982-03-30 US claimed
US-4179537-A ALKOXYSILANES, SUBSTITUTED ALKOXYSILANES RYKOWSKI JOHN J 1979-12-18 US claimed
US-4141926-A Method for preparing epoxy-modified silicon resins SHIN-ETSU CHEMICAL CO., LTD. (JP) 1979-02-27 US claimed
US-4064335-A TITANIUM ANDOR VANADIUM AND ALUMINUM CONTAINING COORDINATION CATALYST THE GOODYEAR TIRE & RUBBER COMPANY (US) 1977-12-20 US claimed
US-4035332-A Water-soluble silicone-modified resin compositions SHIN-ETSU CHEMICAL CO., (JA) 1977-07-12 US claimed
US-4030813-A Control element having liquid layer attainable to geometrically uneven state in response to electrical signal MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. (JA) 1977-06-21 US claimed
US-3959242-A MOLD RELEASE SURFACE THE GOODYEAR TIRE & RUBBER COMPANY (US) 1976-05-25 US claimed