Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 2/20 | 0.39 |
| ▸ | CES1 | P23141 | 2/20 | 0.39 |
| ▸ | GSK3B | P49841 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.35 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.34 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.34 |
| ▸ | MLYCD | O95822 | 5/20 | 0.33 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.33 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.33 |
| ▸ | KCNE1 | P15382 | 1/20 | 0.33 |
| ▸ | KCNQ1 | P51787 | 1/20 | 0.33 |
| ▸ | RORC | P51449 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.32 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.32 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4860261 | 0.83 | SRD5A2 (0.53) | CES2CES1GSK3BALDH1A1SRD5A2 | |
| Hydrochloric Acid SCHEMBL28483241 | 0.81 | SRD5A2 (0.52) | CES2CES1GSK3BALDH1A1SRD5A2 | |
| SCHEMBL9399048 | 0.81 | HPGD (0.44) | CES2CES1GSK3BALDH1A1TRPV1 | |
| SCHEMBL28206212 | 0.81 | MAOB (0.43) | CES2CES1GSK3BALDH1A1MAPT | |
| SCHEMBL7647444 | 0.79 | ESR1 (0.35) | MLYCD | |
| SCHEMBL10575754 | 0.78 | CES2 (0.39) | CES2CES1GSK3BALDH1A1SRD5A2 | |
| SCHEMBL18393922 | 0.76 | CES2 (0.45) | CES2CES1GSK3BALDH1A1SRD5A2 | |
| SCHEMBL103721 | 0.76 | CES2 (0.50) | CES2CES1GSK3BALDH1A1SRD5A2 | |
| SCHEMBL3269101 | 0.76 | ESR1 (0.52) | CES2CES1GSK3BALDH1A1SRD5A2 | |
| SCHEMBL68177 | 0.76 | CES2 (0.67) | CES2CES1GSK3BSRD5A2PTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112625017-B | Amide dianhydride, preparation method and application thereof | 中国科学院长春应用化学研究所 | 2023-12-19 | — | — | CN | disclosed |
| CN-112625017-A | Amide dianhydride, preparation method and application thereof | 中国科学院长春应用化学研究所 | 2021-04-09 | — | — | CN | disclosed |
| EP-0397022-A2 | Polyimide-Polyamide polymers having fluorine-containing linking groups | HOECHST CELANESE CORPORATION (US) | 1990-11-14 | — | — | EP | disclosed |
| US-4962183-A | HEAT, OXIDATION AND SOLVENT RESISTANCE; MOLDING MATERIALS; MELT PROCESSIBILITY; FIBERS, FILMS AND SHEETS | HOECHST CELANESE CORP. (US) | 1990-10-09 | — | — | US | disclosed |