Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.56 |
| ▸ | HPGD | P15428 | 2/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.47 |
| ▸ | HTR2B | P41595 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.47 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30631552 | 0.98 | ALDH1A1 (0.58) | ALDH1A1HPGDCYP1A2CYP2C9CYP2C19 | |
| SCHEMBL16188206 | 0.98 | ALDH1A1 (0.58) | ALDH1A1HPGDCYP1A2CYP2C9CYP2C19 | |
| SCHEMBL3145001 | 0.98 | ALDH1A1 (0.58) | ALDH1A1HPGDCYP1A2CYP2C9CYP2C19 | |
| SCHEMBL15541094 | 0.98 | ALDH1A1 (0.58) | ALDH1A1HPGDCYP1A2CYP2C9CYP2C19 | |
| SCHEMBL2975924 | 0.98 | ALDH1A1 (0.58) | ALDH1A1HPGDCYP1A2CYP2C9CYP2C19 | |
| SCHEMBL6958088 | 0.98 | ALDH1A1 (0.58) | ALDH1A1HPGDCYP1A2CYP2C9CYP2C19 | |
| SCHEMBL1444254 | 0.95 | CYP1A2 (0.55) | ALDH1A1HPGDCYP1A2CYP2C9CYP2C19 | |
| SCHEMBL973234 | 0.89 | ALDH1A1 (0.54) | ALDH1A1HPGDCYP1A2CYP2C9CYP2C19 | |
| Hydrochloric Acid SCHEMBL13857771 | 0.87 | ALDH1A1 (0.53) | ALDH1A1HPGDCYP1A2CYP2C9CYP2C19 | |
| SCHEMBL9808371 | 0.87 | ALDH1A1 (0.48) | ALDH1A1HPGDCYP1A2CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120184565-A1 | COMPOUNDS FOR THE REDUCTION OF BETA-AMYLOID PRODUCTION | BRISTOL-MYERS SQUIBB COMPANY | 2012-07-19 | — | — | US | disclosed |
| CN-1980905-B | An improved process for preparing n-hydroxy-4-{5- [4- (5-isopropyl-2-methyl-l, 3-thiazol-4-yl) -phenoxy] -pentoxy }-benzamidine | DONG WHA PHARM IND CO LTD | 2010-04-21 | — | — | CN | disclosed |
| CN-100562252-C | A kind of herbicidal composition | SINOCHEM CORP SHENYANG RES I O (CN) | 2009-11-25 | — | — | CN | disclosed |
| CN-101433205-A | Herbicide composition | SINOCHEM CORP (CN) | 2009-05-20 | — | — | CN | disclosed |
| EP-1827427-B1 | ARYLOXYETHYLAMINE DERIVATIVES WITH A COMBINATION OF PARTIAL DOPAMINE-D2 RECEPTOR AGONISM AND SEROTONIN REUPTAKE INHIBITION | SOLVAY PHARM BV (NL) | 2008-07-23 | — | — | EP | disclosed |
| CN-101010308-A | Novel benzamidine derivatives, process for the preparation thereof and pharmaceutical composition comprising the same | DONG WHA PHARM IND CO LTD (KR) | 2007-08-01 | — | — | CN | disclosed |
| CN-1980905-A | An improved process for preparing n-hydroxy-4-{5- [4- (5-isopropyl-2-methyl-l, 3-thiazol-4-yl) -phenoxy] -pentoxy }-benzamidine | DONG WHA PHARM IND CO LTD (KR) | 2007-06-13 | — | — | CN | disclosed |
| CN-1105163-C | Liquid crystal compounds, mixtures and devices | SECR DEFENCE (GB) | 2003-04-09 | — | — | CN | disclosed |
| CN-1143382-A | Liquid crystal compounds, mixtures and devices | SECR DEFENCE (GB) | 1997-02-19 | — | — | CN | disclosed |
| CN-1009152-B | Herbicidal compositions containing N- [ (4, 6-dimethoxypyrimidin-2-yl) aminocarbonyl ] -3-trifluoromethylpyridine-2-sulfonamide or salts thereof | ISHIHARA SANGYO KAISHA (JP) | 1990-08-15 | — | — | CN | disclosed |
| CN-85109761-A | N-[(4,6-dimethoxypyridin-2-yl) aminocarboxyl]-production method of 3-5-flumethiazine-2-sulfanilamide (SN) and salt thereof, and the pesticide composition that contains it | — | 1986-12-17 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120184565-A1 | COMPOUNDS FOR THE REDUCTION OF BETA-AMYLOID PRODUCTION | APP, BACE1, IAPP | ALDH1A1 1538/4885HPGD 793/4885CYP1A2 1278/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.