Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 4/20 | 0.53 |
| ▸ | NR5A1 | Q13285 | 1/20 | 0.52 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | CA12 | O43570 | 1/20 | 0.48 |
| ▸ | CA1 | P00915 | 1/20 | 0.48 |
| ▸ | CA2 | P00918 | 1/20 | 0.48 |
| ▸ | CA7 | P43166 | 1/20 | 0.48 |
| ▸ | CA9 | Q16790 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.46 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2238977 | 0.84 | LTA4H (0.55) | LTA4HNR5A1CYP2D6CYP3A4TSHR | |
| SCHEMBL26850 | 0.83 | LTA4H (0.70) | LTA4HNR5A1CYP2D6CYP3A4TSHR | |
| SCHEMBL20306768 | 0.83 | HRH3 (0.53) | NR5A1SMN1; SMN2 | |
| SCHEMBL11070864 | 0.81 | LTA4H (0.52) | LTA4HNR5A1CYP2D6CYP3A4TSHR | |
| SCHEMBL29062602 | 0.79 | NR5A1 (0.63) | LTA4HNR5A1TSHRCA12CA1 | |
| SCHEMBL6288750 | 0.79 | NR5A1 (0.63) | LTA4HNR5A1TSHRCA12CA1 | |
| SCHEMBL29062635 | 0.79 | NR5A1 (0.63) | LTA4HNR5A1TSHRCA12CA1 | |
| 1-Butyloxy-4-Propoxybenzene SCHEMBL23828869 | 0.79 | LTA4H (0.64) | LTA4HNR5A1CYP2D6CYP3A4TSHR | |
| 1-Butyloxy-4-Pentoxybenzene SCHEMBL12827001 | 0.79 | NR5A1 (0.75) | LTA4HNR5A1CYP2D6CYP3A4TSHR | |
| 1,4-Dipropoxybenzene SCHEMBL10846150 | 0.79 | LTA4H (0.64) | LTA4HNR5A1CYP2D6CYP3A4TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8378340-B2 | Aromatic compound | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2013-02-19 | — | — | US | disclosed |
| US-8378340-B2 | Aromatic compound | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2013-02-19 | — | — | US | disclosed |
| US-20120238765-A1 | AROMATIC COMPOUND | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2012-09-20 | — | — | US | disclosed |
| US-8222426-B2 | Aromatic compound | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2012-07-17 | — | — | US | disclosed |
| US-7842941-B2 | Aromatic compound | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2010-11-30 | — | — | US | disclosed |
| US-20100256396-A1 | AROMATIC COMPOUND | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2010-10-07 | — | — | US | disclosed |
| US-20070063190-A1 | Aromatic compound | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2007-03-22 | — | — | US | disclosed |
| US-20070063190-A1 | Aromatic compound | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2007-03-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100256396-A1 | AROMATIC COMPOUND | AHR, AR, NR0B1 | LTA4H 1934/4885NR5A1 11/4885CYP2D6 99/4885 |
| US-20070063190-A1 | Aromatic compound | AHR, AR, NR0B1 | LTA4H 1818/4885NR5A1 10/4885CYP2D6 94/4885 |
| US-20120238765-A1 | AROMATIC COMPOUND | AHR, AR, NR0B1 | LTA4H 1934/4885NR5A1 11/4885CYP2D6 99/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.