Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | SGMS2 | Q8NHU3 | 1/20 | 0.43 |
| ▸ | RXRA | P19793 | 3/20 | 0.42 |
| ▸ | RXRB | P28702 | 3/20 | 0.42 |
| ▸ | RXRG | P48443 | 3/20 | 0.42 |
| ▸ | MRGPRX4 | Q96LA9 | 6/20 | 0.41 |
| ▸ | LIPE | Q05469 | 1/20 | 0.40 |
| ▸ | PTGER1 | P34995 | 2/20 | 0.40 |
| ▸ | PTGER4 | P35408 | 2/20 | 0.40 |
| ▸ | PTGER3 | P43115 | 2/20 | 0.40 |
| ▸ | PTGER2 | P43116 | 2/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27672022 | 0.82 | MAPT (0.45) | MAPTMAPK1TDP1L3MBTL1SGMS2 | |
| SCHEMBL10858144 | 0.82 | MAPT (0.35) | MAPTMRGPRX4 | |
| SCHEMBL10786833 | 0.81 | MAOB (0.44) | MAPTL3MBTL1MAOBKDM4E | |
| SCHEMBL10785722 | 0.78 | BCHE (0.47) | TDP1KDM4EALDH1A1 | |
| SCHEMBL10356139 | 0.75 | RXRA (0.45) | MAPTMAPK1TDP1L3MBTL1SGMS2 | |
| SCHEMBL10889760 | 0.75 | MEN1 (0.43) | MAPTMAPK1L3MBTL1ALDH1A1POLB | |
| SCHEMBL3237142 | 0.74 | MRGPRX4 (0.54) | MAPTMAPK1TDP1L3MBTL1SGMS2 | |
| SCHEMBL12956818 | 0.73 | MRGPRX4 (0.41) | MAPTMAPK1TDP1L3MBTL1SGMS2 | |
| SCHEMBL14228414 | 0.73 | MAPT (0.56) | MAPTMAPK1TDP1L3MBTL1RXRA | |
| SCHEMBL14453588 | 0.73 | MRGPRX4 (0.50) | MAPTMAPK1TDP1L3MBTL1SGMS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0126013-B1 | CYCLIC DITHIOACETAMIDES, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | SANOFI S.A. (FR) | 1987-09-23 | — | — | EP | claimed |
| EP-0116787-B1 | 1,1-DIPHENYLPROPANOL DERIVATIVES, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | Richter Gedeon Vegyészeti Gyár R.T. (HU) | 1987-03-18 | — | — | EP | claimed |
| US-4605785-A | I(DUCE POLYSUBSTRATE MONOOXYGENASE ENZYME SYSTEM OF LIV)R WI HOUT GENTS | RICHTER GEDEON VEGYESZETI GYAR RT (HU) | 1986-08-12 | — | — | US | claimed |
| EP-0116787-A1 | 1,1-Diphenylpropanol derivatives, process for their preparation and pharmaceutical compositions containing them | Richter Gedeon Vegyészeti Gyár R.T. (HU) | 1984-08-29 | — | — | EP | claimed |
| EP-0179662-B1 | FODDER ADDITIVE AND A PROCESS FOR THE PREPARATION THEREOF | RICHTER GEDEON VEGYESZET (HU) | 1990-10-03 | — | — | EP | disclosed |
| US-4659712-A | ELIMINATION OF METABOLITES FROM LIVER | RICHTER GEDEON VEGYESZETI GYAR RT. (HU) | 1987-04-21 | — | — | US | disclosed |
| EP-0116787-B1 | 1,1-DIPHENYLPROPANOL DERIVATIVES, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | Richter Gedeon Vegyészeti Gyár R.T. (HU) | 1987-03-18 | — | — | EP | disclosed |
| US-4605785-A | I(DUCE POLYSUBSTRATE MONOOXYGENASE ENZYME SYSTEM OF LIV)R WI HOUT GENTS | RICHTER GEDEON VEGYESZETI GYAR RT (HU) | 1986-08-12 | — | — | US | disclosed |
| EP-0179662-A2 | Fodder additive and a process for the preparation thereof | RICHTER GEDEON VEGYESZETI GYAR R.T. (HU) | 1986-04-30 | — | — | EP | disclosed |
| EP-0116787-A1 | 1,1-Diphenylpropanol derivatives, process for their preparation and pharmaceutical compositions containing them | Richter Gedeon Vegyészeti Gyár R.T. (HU) | 1984-08-29 | — | — | EP | disclosed |