SCHEMBL10356552

SCHEMBL10356552

COC([SiH3])(OC)OCCC(C)C

nearest known ligand 0.34

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.34
CA12 O43570 1/20 0.31
CA1 P00915 1/20 0.31
CA2 P00918 1/20 0.31
CA9 Q16790 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10629439 0.79 ALDH1A1 (0.33) ALDH1A1CA12CA1CA2CA9
SCHEMBL18636634 0.73 ALDH1A1 (0.36) ALDH1A1CA12CA1CA2CA9
SCHEMBL31755 0.69 MAPK1 (0.42) ALDH1A1CA12CA1CA2CA9
SCHEMBL12982357 0.67 ALDH1A1 (0.39) ALDH1A1CA12CA1CA2CA9
SCHEMBL895937 0.67 ALDH1A1 (0.39) ALDH1A1CA12CA1CA2CA9
SCHEMBL10356764 0.67 RECQL (0.34) CA12CA1CA2CA9
SCHEMBL9314091 0.67 ODC1 (0.36)
SCHEMBL16918290 0.65 CA12 (0.38) ALDH1A1CA12CA1CA2CA9
SCHEMBL16363513 0.65 ALDH1A1 (0.37) ALDH1A1CA12CA1CA2CA9
SCHEMBL12695724 0.65 ALDH1A1 (0.37) ALDH1A1CA12CA1CA2CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0212063-B1 URETHANE RESINS CONTAINING HYDROLYZABLE MOIETIES FROM ORGANOSILANE COMPOUNDS PPG INDUSTRIES, INC. (US) 1990-09-05 EP disclosed
US-4913972-A Transparent coating system for providing long term exterior durability to wood PPG INDUSTRIES, INC. (US) 1990-04-03 US disclosed
US-4808663-A FOR LOW TEMPERATURE, MOISTURE, CATALYTIC CURING COATINGS PPG INDUSTRIES, INC. (US) 1989-02-28 US disclosed
US-4788107-A ADHESIVES, SEALANTS, INKS PPG INDUSTRIES, INC. (US) 1988-11-29 US disclosed
EP-0278305-A1 Transparent coating system for providing long term exterior durability to wood PPG INDUSTRIES, INC. (US) 1988-08-17 EP disclosed
US-4714738-A CURABLE AT LOW TEMPERATURE PPG INDUSTRIES, INC. (US) 1987-12-22 US disclosed
EP-0234308-A2 Coating composition containing an ungelled reaction product as a curative PPG INDUSTRIES, INC. (US) 1987-09-02 EP disclosed
EP-0231514-A2 Compositions based on resins having silicon atoms attached to hydrolyzable groups derived from vinyl silanes and mercaptofunctional compounds PPG INDUSTRIES, INC. (US) 1987-08-12 EP disclosed
US-4678835-A AMINE AND SILICON-CONTAINING PPG INDUSTRIES, INC. (US) 1987-07-07 US disclosed
EP-0216320-A2 Compositions containing resins having air-oxidizable groups and epoxy groups and epoxy-reactive silicon-containing compounds having hydrolyzable groups PPG INDUSTRIES, INC. (US) 1987-04-01 EP disclosed
US-4652610-A FLEXIBLE COATINGS; AUTOMOBILE PAINTS PPG INDUSTRIES, INC. (US) 1987-03-24 US disclosed
EP-0212063-A1 Urethane resins containing hydrolyzable moieties from organosilane compounds PPG INDUSTRIES, INC. (US) 1987-03-04 EP disclosed
EP-0205827-A2 Acrylic polymers containing hydrolyzable moieties from organosilane compounds PPG INDUSTRIES, INC. (US) 1986-12-30 EP disclosed
EP-0203391-A2 Ungelled resins containing hydrolyzable moieties from organosilane compounds PPG INDUSTRIES, INC. (US) 1986-12-03 EP disclosed
US-4623697-A Ungelled resins containing hydrolyzable moieties from organosilane compounds PPG INDUSTRIES, INC. (US) 1986-11-18 US disclosed
US-4622369-A Urethane resins containing hydrolyzable moieties from organosilane compounds PPG INDUSTRIES, INC. (US) 1986-11-11 US disclosed
US-4614766-A Compositions containing resins having air-oxidizable groups and epoxy groups and epoxy-reactive silicon-containing compounds having hydrolyzable groups PPG INDUSTRIES, INC. (US) 1986-09-30 US disclosed