SCHEMBL10357197

SCHEMBL10357197

CCCCOC(OCCCC)C(CCCNC(=N)N)NC(=O)CN

nearest known ligand 0.33

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
▸ DPP7 Q9UHL4 2/20 0.33
▸ TLR2 O60603 3/20 0.33
▸ RRM1 P23921 1/20 0.33
▸ ACHE P22303 1/20 0.32
▸ MAPT P10636 2/20 0.32
▸ HSD17B10 Q99714 1/20 0.32
▸ SIRT6 Q8N6T7 1/20 0.32
▸ SIRT1 Q96EB6 1/20 0.32
▸ ITGB3 P05106 2/20 0.32
▸ ITGA2B P08514 2/20 0.32
▸ GNAI3 P08754 1/20 0.32
▸ GNAO1 P09471 1/20 0.32
▸ GNAI1 P63096 1/20 0.32
▸ EPHX2 P34913 1/20 0.31
▸ TSHR P16473 1/20 0.31
▸ RECQL P46063 1/20 0.31
▸ SPHK1 Q9NYA1 3/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10357194 1.00 DPP7 (0.33) DPP7TLR2RRM1ACHEMAPT
Hydrochloric Acid SCHEMBL7412361 0.99 TLR2 (0.34) DPP7TLR2RRM1ACHEMAPT
SCHEMBL10358107 0.82 DPP7 (0.36) DPP7RRM1MAPTHSD17B10
SCHEMBL10357838 0.82 DPP7 (0.36) DPP7RRM1MAPTHSD17B10
SCHEMBL10357832 0.82 DPP7 (0.36) DPP7RRM1MAPTHSD17B10
SCHEMBL10358160 0.82 DPP7 (0.36) DPP7RRM1MAPTHSD17B10
SCHEMBL10358109 0.82 DPP7 (0.36) DPP7RRM1MAPTHSD17B10
SCHEMBL7450049 0.81 ACHE (0.40) ACHEMAPTHSD17B10TSHR
SCHEMBL8358758 0.80 NPY4R (0.41) DPP7RRM1MAPTHSD17B10
SCHEMBL14269796 0.80 NPY4R (0.41) DPP7RRM1MAPTHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0167152-B1 PROTEASE ADSORBENT AND PROCESS FOR PURIFYING TPA UTILIZING THE SAME NIPPON KAYAKU KABUSHIKI KAISHA (JP) 1990-11-14 — — EP disclosed
US-4708944-A Protease adsorbent and process for purifying TPA utilizing the same NIPPON KAYAKU KABUSHIKI KAISHA (JP) 1987-11-24 — — US disclosed
EP-0167152-A2 Protease adsorbent and process for purifying TPA utilizing the same NIPPON KAYAKU KABUSHIKI KAISHA (JP) 1986-01-08 — — EP disclosed
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