Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.59 |
| ▸ | MEN1 | O00255 | 3/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.59 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.52 |
| ▸ | ERN1 | O75460 | 1/20 | 0.49 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL272154 | 0.86 | ERN1 (0.57) | TDP1ALDH1A1MEN1KMT2AERN1 | |
| SCHEMBL9775507 | 0.83 | HSP90AA1 (0.50) | TDP1ALDH1A1MEN1KMT2AHSP90AA1 | |
| SCHEMBL25529539 | 0.83 | HSP90AA1 (0.50) | TDP1ALDH1A1MEN1KMT2AHSP90AA1 | |
| SCHEMBL25201635 | 0.80 | HSP90AA1 (0.51) | TDP1ALDH1A1MEN1KMT2AHSP90AA1 | |
| SCHEMBL8517220 | 0.80 | HSP90AA1 (0.47) | TDP1ALDH1A1MEN1KMT2AHSP90AA1 | |
| SCHEMBL701358 | 0.79 | MEN1 (0.49) | TDP1ALDH1A1MEN1KMT2AHSP90AA1 | |
| SCHEMBL701357 | 0.79 | MEN1 (0.49) | TDP1ALDH1A1MEN1KMT2AHSP90AA1 | |
| SCHEMBL22918190 | 0.78 | ERN1 (0.65) | TDP1ALDH1A1MEN1KMT2AERN1 | |
| SCHEMBL1619153 | 0.78 | ERN1 (0.50) | TDP1ALDH1A1MEN1KMT2AHSP90AA1 | |
| SCHEMBL31339796 | 0.78 | ERN1 (0.50) | TDP1ALDH1A1MEN1KMT2AHSP90AA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 634 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220257483-A1 | INCREASING THE STABILITY OF AGENTS FOR TREATING KERATIN MATERIAL | HENKEL AG & CO. KGAA (DE) | 2022-08-18 | — | — | US | claimed |
| EP-4003286-A1 | INCREASING THE STABILITY OF AGENTS FOR TREATING KERATIN MATERIAL | Henkel AG & Co. KGaA (DE) | 2022-06-01 | — | — | EP | claimed |
| CN-114173750-A | Improving the stability of agents for treating keratin materials | 汉高股份有限及两合公司 | 2022-03-11 | — | — | CN | claimed |
| WO-2021013420-A1 | INCREASING THE STABILITY OF AGENTS FOR TREATING KERATIN MATERIAL | HENKEL AG & CO. KGAA (DE) | 2021-01-28 | — | — | WO | claimed |
| CN-107903217-A | A kind of preparation method of anagrelide impurity B | 湖北省宏源药业科技股份有限公司 | 2018-04-13 | — | — | CN | claimed |
| CN-102757350-A | Preparation method of erlotinib intermediate, i.e., 3-aminobenzeneacetylene | Suzhou lixin pharmaceutical co ltd | 2012-10-31 | — | — | CN | claimed |
| EP-1778176-B1 | COMPOSITION FOR COLOURING KERATIN-CONTAINING FIBRES | HENKEL AG & CO KGAA (DE) | 2012-07-25 | — | — | EP | claimed |
| US-7678156-B2 | Compositions for treating keratinic fibers, methods of treating such fibers therewith and compounds contained therein | HENKEL AG & CO. KGAA (DE) | 2010-03-16 | — | — | US | claimed |
| EP-1796627-B1 | AGENT FOR COLOURING FIBRES CONTAINING KERATIN | HENKEL AG & CO KGAA (DE) | 2009-03-04 | — | — | EP | claimed |
| EP-2018844-A2 | Agent for dying fibres which contain keratin comprising derivatives of naphthaldehyde in combination with CH acidic compounds | Henkel AG & Co. KGaA (DE) | 2009-01-28 | — | — | EP | claimed |
| EP-1432388-A1 | AGENT FOR COLOURING FIBRES CONTAINING KERATIN | Henkel Kommanditgesellschaft auf Aktien (DE) | 2004-06-30 | — | — | EP | claimed |
| WO-2004022016-A1 | AGENTS USED FOR DYEING KERATINOUS FIBERS | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 2004-03-18 | — | — | WO | claimed |
| WO-2003030845-A1 | AGENT FOR THE COLORATION OF KERATIN-CONTAINING FIBERS | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 2003-04-17 | — | — | WO | claimed |
| WO-2003030847-A1 | AGENT FOR COLOURING FIBRES CONTAINING KERATIN | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 2003-04-17 | — | — | WO | claimed |
| WO-2003030842-A1 | AGENT FOR COLOURING FIBRES CONTAINING KERATIN | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 2003-04-17 | — | — | WO | claimed |
| EP-1300133-A2 | Agent for dyeing keratinous fibres | Henkel Kommanditgesellschaft auf Aktien (DE) | 2003-04-09 | — | — | EP | claimed |
| EP-1300132-A2 | Agent for dyeing keratinous fibres | Henkel Kommanditgesellschaft auf Aktien (DE) | 2003-04-09 | — | — | EP | claimed |
| WO-2000038634-A1 | AGENT FOR DYING KERATIN FIBERS | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 2000-07-06 | — | — | WO | claimed |
| US-4380629-A | Styryl-like compounds showing a color-developing and bleaching behavior with improved stability and prolonged lifetime | MATSUSHITA ELECTRIC INDUSTRIAL COMPANY, LIMITED (JP) | 1983-04-19 | — | — | US | claimed |
| US-4147862-A | Method of preparing styryl-like compounds | MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. (JP) | 1979-04-03 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220257483-A1 | INCREASING THE STABILITY OF AGENTS FOR TREATING KERATIN MATERIAL | KRT18, VIM, CDH1 | TDP1 3850/4885ALDH1A1 143/4885MEN1 1333/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.