Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | HTT | P42858 | 2/20 | 0.48 |
| ▸ | TBXA2R | P21731 | 2/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.45 |
| ▸ | HPGD | P15428 | 3/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | BDKRB1 | P46663 | 1/20 | 0.45 |
| ▸ | KCNA5 | P22460 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | STAT3 | P40763 | 1/20 | 0.43 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10358270 | 0.91 | CYP1A2 (0.56) | CYP1A2ALDH1A1HTTTBXA2RALOX15 | |
| SCHEMBL10357552 | 0.90 | CYP1A2 (0.51) | CYP1A2ALDH1A1HTTTBXA2RALOX15 | |
| SCHEMBL10357581 | 0.90 | CYP1A2 (0.51) | CYP1A2ALDH1A1HTTTBXA2RALOX15 | |
| SCHEMBL10358326 | 0.87 | PPARD (0.50) | CYP1A2ALDH1A1HTTALOX15TSHR | |
| SCHEMBL10462970 | 0.87 | MAPT (0.51) | CYP1A2ALDH1A1HTTALOX15TSHR | |
| SCHEMBL10549765 | 0.84 | KDM4C (0.50) | ALDH1A1ALOX15TSHRHSD17B10MEN1 | |
| SCHEMBL10592429 | 0.82 | PPARG (0.47) | ALDH1A1TBXA2RHPGDPOLBGLA | |
| SCHEMBL10357321 | 0.81 | CA1 (0.49) | CYP1A2ALDH1A1HTTTBXA2RMEN1 | |
| SCHEMBL10464117 | 0.81 | PDE4A (0.49) | CYP1A2ALDH1A1HTTMEN1KMT2A | |
| SCHEMBL251462 | 0.79 | CA1 (0.47) | CYP1A2ALDH1A1HTTTBXA2RMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0253257-B1 | SUBSTITUTED AMINO-5,6,7,8-TETRAHYDRONAPHTHYL-OXYACETIC ACIDS, METHOD FOR THEIR PREPARATION AND THEIR APPLICATION AS MEDICAMENTS | BAYER AG (DE) | 1990-11-14 | — | — | EP | disclosed |
| US-4921998-A | ANTICOAGULANTS, ANTIISCHEMIC AGENTS, ATHEROSCLEROSIS | BAYER AKTIENGESELLSCHAFT (DE) | 1990-05-01 | — | — | US | disclosed |
| US-4868331-A | ANTICOAGULANTS, ANTIATHEROSCLEROTIC, ANTIISCHEMIC | BAYER AKTIENGESELLSCHAFT (DE) | 1989-09-19 | — | — | US | disclosed |
| EP-0253257-A2 | Substituted amino-5,6,7,8-tetrahydronaphthyl-oxyacetic acids, method for their preparation and their application as medicaments | BAYER AG (DE) | 1988-01-20 | — | — | EP | disclosed |