Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4C | Q9H3R0 | 11/20 | 0.50 |
| ▸ | HTR6 | P50406 | 6/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | KDM6B | O15054 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10551358 | 0.91 | HTR6 (0.53) | KDM4CHTR6ALOX15TSHRHSD17B10 | |
| SCHEMBL10550733 | 0.90 | HTR6 (0.49) | KDM4CHTR6 | |
| SCHEMBL10550118 | 0.90 | HTR6 (0.46) | KDM4CHTR6ALOX15TSHRHSD17B10 | |
| SCHEMBL10564090 | 0.88 | PPARD (0.52) | KDM4CHTR6ALOX15TSHRHSD17B10 | |
| SCHEMBL10553512 | 0.87 | HTR6 (0.44) | KDM4CHTR6ALOX15TSHRHSD17B10 | |
| SCHEMBL10550518 | 0.85 | HTR6 (0.46) | KDM4CHTR6ALOX15TSHRHSD17B10 | |
| SCHEMBL10357654 | 0.84 | CYP1A2 (0.51) | ALOX15TSHRHSD17B10MEN1ALDH1A1 | |
| SCHEMBL10596417 | 0.83 | FFAR1 (0.48) | KDM4CFFAR1MEN1ALDH1A1CYP2C9 | |
| SCHEMBL10553988 | 0.83 | HTR6 (0.56) | KDM4CHTR6 | |
| SCHEMBL10550905 | 0.82 | PTGIR (0.52) | KDM4CHSD17B10MEN1ALDH1A1CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4886898-A | THROMOBOXANE ANTAGONISTS | BAYER AKTIENGESELLSCHAFT (DE) | 1989-12-12 | — | — | US | disclosed |
| US-4868332-A | ANTITHROMBOTIC, ANTIATHEROSCLEROTIC, ANTIISCHEMIC | BAYER AKTIENGESELLSCHAFT (DE) | 1989-09-19 | — | — | US | disclosed |