SCHEMBL10358043

SCHEMBL10358043

O=C(C=Cc1ccc(C(=O)O)cc1)C=Cc1ccc(C(=O)O)cc1

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 4/20 0.64
F3 P13726 4/20 0.64
CYP2D6 P10635 3/20 0.64
CYP2C9 P11712 2/20 0.64
ALDH1A1 P00352 2/20 0.64
MAPT P10636 2/20 0.64
SMN1; SMN2 Q16637 2/20 0.64
PLIN1 O60240 1/20 0.64
LMNA P02545 1/20 0.64
RECQL P46063 1/20 0.64
PLIN5 Q00G26 1/20 0.64
ABHD5 Q8WTS1 1/20 0.64
HSD11B1 P28845 2/20 0.61
TYR P14679 1/20 0.61
XDH P47989 1/20 0.56
FBP1 P09467 1/20 0.55
TP53 P04637 2/20 0.55
TSHR P16473 1/20 0.55
JUN P05412 1/20 0.54
NFKB1 P19838 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14922834 1.00 CYP1A2 (0.64) CYP1A2F3CYP2D6CYP2C9ALDH1A1
SCHEMBL10358042 1.00 CYP1A2 (0.64) CYP1A2F3CYP2D6CYP2C9ALDH1A1
Benzoic Acid SCHEMBL27142490 0.87 MAPT (0.79) CYP1A2F3CYP2D6CYP2C9ALDH1A1
SCHEMBL70241 0.86 HCAR2 (0.65) CYP2D6CYP2C9ALDH1A1MAPTSMN1; SMN2
SCHEMBL70240 0.86 HCAR2 (0.65) CYP2D6CYP2C9ALDH1A1MAPTSMN1; SMN2
SCHEMBL69167 0.85 ALDH1A1 (0.68) CYP2D6ALDH1A1SMN1; SMN2TYRXDH
SCHEMBL9681086 0.85 ALDH1A1 (0.68) CYP2D6ALDH1A1SMN1; SMN2TYRXDH
SCHEMBL9681088 0.85 ALDH1A1 (0.68) CYP2D6ALDH1A1SMN1; SMN2TYRXDH
SCHEMBL2615887 0.85 ALDH1A1 (0.68) CYP2D6ALDH1A1SMN1; SMN2TYRXDH
SCHEMBL9339856 0.85 ALDH1A1 (0.68) CYP2D6ALDH1A1SMN1; SMN2TYRXDH

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0177793-B1 PROCESS FOR PREPARING POLYAMIDES Asahi Kasei Kogyo Kabushiki Kaisha (JP) 1990-11-28 EP disclosed
US-4754016-A Process for preparing polyamide with organic phosphine/organic disulfide mixture condensing agent ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) 1988-06-28 US disclosed
EP-0248932-A1 Process for preparing polyamides Asahi Kasei Kogyo Kabushiki Kaisha (JP) 1987-12-16 EP disclosed
US-4645823-A CORROSION RESISTANCE; NONTOXIC ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) 1987-02-24 US disclosed
EP-0177793-A2 Process for preparing polyamides Asahi Kasei Kogyo Kabushiki Kaisha (JP) 1986-04-16 EP disclosed