Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.59 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.59 |
| ▸ | EBP | Q15125 | 1/20 | 0.54 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 2/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | SMARCA2 | P51531 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.54 |
| ▸ | MAOB | P27338 | 1/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | LTA4H | P09960 | 1/20 | 0.53 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10358381 | 0.85 | KDM4E (0.65) | MAPTKMT2ACHRNA7EBPSIGMAR1 | |
| SCHEMBL9706125 | 0.82 | EBP (0.72) | MAPTKMT2ACHRNA7EBPSIGMAR1 | |
| SCHEMBL13091437 | 0.81 | HRH3 (0.55) | MAPTKMT2AKDM4ESMN1; SMN2LTA4H | |
| SCHEMBL3763682 | 0.80 | DRD2 (0.58) | MAPTKMT2AKDM4EHTTSMN1; SMN2 | |
| SCHEMBL3420518 | 0.79 | EBP (0.64) | MAPTKMT2ACHRNA7EBPSIGMAR1 | |
| SCHEMBL9706141 | 0.79 | KDM4E (0.73) | MAPTKMT2ACHRNA7EBPSIGMAR1 | |
| SCHEMBL469900 | 0.79 | DRD2 (0.53) | MAPTKMT2AKDM4EHTTSMN1; SMN2 | |
| SCHEMBL11365687 | 0.79 | DRD2 (0.57) | MAPTKMT2AKDM4ETSHRHTT | |
| SCHEMBL30969307 | 0.79 | MAOB (0.61) | MAPTKMT2ACHRNA7EBPSIGMAR1 | |
| SCHEMBL9357458 | 0.79 | MAOB (0.61) | MAPTKMT2ACHRNA7EBPSIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0109563-B1 | METHOD OF INCREASING BIOMASS IN PLANTS | US AGRICULTURE (US) | 1990-10-10 | — | — | EP | claimed |
| US-4797153-A | PLANT GROWTH REGULATORS | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF AGRICULTURE (US) | 1989-01-10 | — | — | US | claimed |
| EP-0109563-A2 | Method of increasing biomass in plants | THE UNITED STATES OF AMERICA as represented by the Secretary United States Department of Commerce (US) | 1984-05-30 | — | — | EP | claimed |
| WO-1984001489-A1 | METHOD OF INCREASING BIOMASS IN PLANTS | US AGRICULTURE (US) | 1984-04-26 | — | — | WO | claimed |
| US-20070161677-A1 | Bisarylurea derivatives | MERCK PATENT GMBH (DE) | 2007-07-12 | — | — | US | disclosed |
| EP-0109563-B1 | METHOD OF INCREASING BIOMASS IN PLANTS | US AGRICULTURE (US) | 1990-10-10 | — | — | EP | disclosed |
| US-4797153-A | PLANT GROWTH REGULATORS | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF AGRICULTURE (US) | 1989-01-10 | — | — | US | disclosed |
| EP-0109563-A2 | Method of increasing biomass in plants | THE UNITED STATES OF AMERICA as represented by the Secretary United States Department of Commerce (US) | 1984-05-30 | — | — | EP | disclosed |
| WO-1984001489-A1 | METHOD OF INCREASING BIOMASS IN PLANTS | US AGRICULTURE (US) | 1984-04-26 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070161677-A1 | Bisarylurea derivatives | BRAF, RAF1, NRAS | MAPT 2288/4885KMT2A 1891/4885CHRNA7 4783/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.