⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL721746 | 0.84 | — | — | |
| SCHEMBL9683555 | 0.76 | — | — | |
| SCHEMBL9790193 | 0.75 | — | — | |
| SCHEMBL10357363 | 0.71 | — | — | |
| SCHEMBL1104606 | 0.65 | — | — | |
| SCHEMBL1223591 | 0.64 | — | — | |
| SCHEMBL8608160 | 0.63 | — | — | |
| SCHEMBL3296616 | 0.62 | ALDH1A1 (0.38) | — | |
| SCHEMBL4450395 | 0.62 | CHRM2 (0.45) | — | |
| SCHEMBL11931643 | 0.61 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0184692-B1 | METHOD OF PREPARATION OF O-SILYLATED KETENE ACETALS AND ENOL ETHERS | UNION CARBIDE CORPORATION (US) | 1990-12-27 | — | — | EP | disclosed |
| US-4780554-A | O-silylated ketene acetals and enol ethers and method of preparation | UNION CARBIDE CORPORATION (US) | 1988-10-25 | — | — | US | disclosed |
| EP-0184692-A1 | Method of preparation of o-silylated ketene acetals and enol ethers | UNION CARBIDE CORPORATION (US) | 1986-06-18 | — | — | EP | disclosed |