Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 3/20 | 0.62 |
| ▸ | HTT | P42858 | 1/20 | 0.62 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.52 |
| ▸ | MAOB | P27338 | 8/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6606515 | 0.83 | MAOB (0.56) | RAB9AHTTL3MBTL1ALDH1A1KMT2A | |
| SCHEMBL13883739 | 0.82 | MAOB (0.64) | RAB9AHTTL3MBTL1ALDH1A1KMT2A | |
| SCHEMBL23733022 | 0.82 | RAB9A (0.62) | RAB9AHTTL3MBTL1ALDH1A1KMT2A | |
| SCHEMBL7162438 | 0.81 | MAOB (0.62) | RAB9AHTTL3MBTL1ALDH1A1KMT2A | |
| SCHEMBL21086834 | 0.80 | TDP1 (0.57) | RAB9AHTTL3MBTL1KMT2ACYP1A2 | |
| SCHEMBL1438757 | 0.79 | MAOB (0.56) | RAB9AHTTL3MBTL1ALDH1A1KMT2A | |
| SCHEMBL30049851 | 0.79 | KDM4E (0.56) | RAB9AHTTL3MBTL1ALDH1A1KMT2A | |
| SCHEMBL23732573 | 0.79 | KDM4E (0.56) | RAB9AHTTL3MBTL1ALDH1A1KMT2A | |
| SCHEMBL2801030 | 0.79 | MAOB (0.60) | RAB9AHTTL3MBTL1ALDH1A1KMT2A | |
| SCHEMBL30628305 | 0.79 | RAB9A (0.40) | RAB9AHTTL3MBTL1KMT2AMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0262188-B1 | STEROIDS COMPRISING A SPIRANIC CYCLE IN POSITION 17, PREPARATION PROCESS AND UTILIZATION THEREOF | ROUSSEL-UCLAF (FR) | 1990-11-14 | — | — | EP | disclosed |
| US-4900725-A | CONTRACEPTIVES | ROUSSEL UCLAF (FR) | 1990-02-13 | — | — | US | disclosed |
| EP-0262188-A1 | STEROIDS COMPRISING A SPIRANIC CYCLE IN POSITION 17, PREPARATION PROCESS AND UTILIZATION THEREOF. | ROUSSEL UCLAF (FR) | 1988-04-06 | — | — | EP | disclosed |
| WO-1987005908-A1 | STEROIDS COMPRISING A SPIRANIC CYCLE IN POSITION 17, PREPARATION PROCESS AND UTILIZATION THEREOF | ROUSSEL-UCLAF (FR) | 1987-10-08 | — | — | WO | disclosed |