Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 2/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.36 |
| ▸ | MAPT | P10636 | 5/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.35 |
| ▸ | KDM1A | O60341 | 1/20 | 0.35 |
| ▸ | MAOA | P21397 | 1/20 | 0.35 |
| ▸ | ACP3 | P15309 | 1/20 | 0.33 |
| ▸ | FAAH | O00519 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.31 |
| ▸ | HPGD | P15428 | 4/20 | 0.31 |
| ▸ | TP53 | P04637 | 3/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.31 |
| ▸ | LMNA | P02545 | 3/20 | 0.31 |
| ▸ | USP2 | O75604 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8822879 | 0.82 | ACP3 (0.36) | EPHX1CYP3A4MAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL9639884 | 0.70 | ESR1 (0.34) | CYP3A4MAPTALDH1A1SMN1; SMN2CYP1A2 | |
| SCHEMBL9639422 | 0.69 | CYP3A4 (0.33) | CYP3A4MAPTALDH1A1SMN1; SMN2CYP1A2 | |
| SCHEMBL4664940 | 0.68 | — | — | |
| SCHEMBL8305215 | 0.66 | EPHX1 (0.45) | EPHX1CYP3A4ALDH1A1CYP1A2KMT2A | |
| SCHEMBL8308522 | 0.66 | EPHX1 (0.45) | EPHX1CYP3A4ALDH1A1CYP1A2KMT2A | |
| SCHEMBL7294198 | 0.64 | EPHX1 (0.55) | EPHX1CYP3A4ALDH1A1KDM4EKMT2A | |
| SCHEMBL10359199 | 0.63 | — | — | |
| SCHEMBL19144912 | 0.62 | IDO1 (0.64) | EPHX1SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL24768311 | 0.59 | CHRNB4 (0.56) | CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0247320-B1 | 5-ARYLALKYL-4-ALKOXY-2(5H)-FURANONES, INTERMEDIATES AND PROCESS FOR THEIR PREPARATION AS WELL AS THEIR APPLICATION AS THERAPEUTICALLY ACTIVE INGREDIENTS | SCHWABE WILLMAR GMBH & CO (DE) | 1990-12-27 | — | — | EP | claimed |
| US-4855320-A | ANTICONVULSANTS, ANTIEPILEPTICS | DR. WILLMAR SCHWABE GMBH & COMPANY (DE) | 1989-08-08 | — | — | US | claimed |
| EP-0247320-A2 | 5-Arylalkyl-4-alkoxy-2(5H)-furanones, intermediates and process for their preparation as well as their application as therapeutically active ingredients | Dr. Willmar Schwabe GmbH & Co. (DE) | 1987-12-02 | — | — | EP | claimed |
| EP-0247320-B1 | 5-ARYLALKYL-4-ALKOXY-2(5H)-FURANONES, INTERMEDIATES AND PROCESS FOR THEIR PREPARATION AS WELL AS THEIR APPLICATION AS THERAPEUTICALLY ACTIVE INGREDIENTS | SCHWABE WILLMAR GMBH & CO (DE) | 1990-12-27 | — | — | EP | disclosed |
| US-4855320-A | ANTICONVULSANTS, ANTIEPILEPTICS | DR. WILLMAR SCHWABE GMBH & COMPANY (DE) | 1989-08-08 | — | — | US | disclosed |