Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.80 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.80 |
| ▸ | MAPT | P10636 | 3/20 | 0.80 |
| ▸ | LMNA | P02545 | 2/20 | 0.80 |
| ▸ | TSHR | P16473 | 2/20 | 0.80 |
| ▸ | BLM | P54132 | 2/20 | 0.80 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.80 |
| ▸ | MEN1 | O00255 | 2/20 | 0.80 |
| ▸ | MPO | P05164 | 1/20 | 0.80 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.80 |
| ▸ | HTR1A | P08908 | 2/20 | 0.67 |
| ▸ | HTR2A | P28223 | 2/20 | 0.67 |
| ▸ | HTR2C | P28335 | 2/20 | 0.67 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.67 |
| ▸ | HTR7 | P34969 | 2/20 | 0.67 |
| ▸ | HTR2B | P41595 | 2/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.67 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.67 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.67 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.67 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Dl-Tryptophan SCHEMBL27153674 | 1.00 | KMT2A (0.80) | KMT2AKDM4EMAPTLMNATSHR | |
| Dl-Tryptophan SCHEMBL243573 | 1.00 | KMT2A (0.80) | KMT2AKDM4EMAPTLMNATSHR | |
| D-Tryptophan SCHEMBL10359011 | 1.00 | KMT2A (0.80) | KMT2AKDM4EMAPTLMNATSHR | |
| Tryptophan SCHEMBL15168746 | 1.00 | KMT2A (0.80) | KMT2AKDM4EMAPTLMNATSHR | |
| Tryptophan SCHEMBL6032938 | 1.00 | KMT2A (0.80) | KMT2AKDM4EMAPTLMNATSHR | |
| Tryptophan SCHEMBL243574 | 1.00 | KMT2A (0.80) | KMT2AKDM4EMAPTLMNATSHR | |
| Dl-Tryptophan SCHEMBL152717 | 0.99 | KMT2A (0.78) | KMT2AKDM4EMAPTLMNATSHR | |
| Tryptophan SCHEMBL325026 | 0.99 | KMT2A (0.78) | KMT2AKDM4EMAPTLMNATSHR | |
| Dl-Tryptophan SCHEMBL27561249 | 0.99 | KMT2A (0.78) | KMT2AKDM4EMAPTLMNATSHR | |
| Tryptophan SCHEMBL9449482 | 0.95 | KDM4E (0.73) | KMT2AKDM4EMAPTLMNATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0215171-B1 | PEPTIDES | THE ADMINISTRATORS OF THE TULANE UNIVERSITY EDUCATIONAL FUND (US) | 1990-11-22 | — | — | EP | claimed |