Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.80 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.80 |
| ▸ | MAPT | P10636 | 3/20 | 0.80 |
| ▸ | LMNA | P02545 | 2/20 | 0.80 |
| ▸ | TSHR | P16473 | 2/20 | 0.80 |
| ▸ | BLM | P54132 | 2/20 | 0.80 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.80 |
| ▸ | MEN1 | O00255 | 2/20 | 0.80 |
| ▸ | MPO | P05164 | 1/20 | 0.80 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.80 |
| ▸ | HTR1A | P08908 | 2/20 | 0.67 |
| ▸ | HTR2A | P28223 | 2/20 | 0.67 |
| ▸ | HTR2C | P28335 | 2/20 | 0.67 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.67 |
| ▸ | HTR7 | P34969 | 2/20 | 0.67 |
| ▸ | HTR2B | P41595 | 2/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.67 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.67 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.67 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.67 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Dl-Tryptophan SCHEMBL27153674 | 1.00 | KMT2A (0.80) | KMT2AKDM4EMAPTLMNATSHR | |
| Dl-Tryptophan SCHEMBL243573 | 1.00 | KMT2A (0.80) | KMT2AKDM4EMAPTLMNATSHR | |
| D-Tryptophan SCHEMBL10359011 | 1.00 | KMT2A (0.80) | KMT2AKDM4EMAPTLMNATSHR | |
| D-Tryptophan SCHEMBL10359012 | 1.00 | KMT2A (0.80) | KMT2AKDM4EMAPTLMNATSHR | |
| Tryptophan SCHEMBL15168746 | 1.00 | KMT2A (0.80) | KMT2AKDM4EMAPTLMNATSHR | |
| Tryptophan SCHEMBL6032938 | 1.00 | KMT2A (0.80) | KMT2AKDM4EMAPTLMNATSHR | |
| Dl-Tryptophan SCHEMBL152717 | 0.99 | KMT2A (0.78) | KMT2AKDM4EMAPTLMNATSHR | |
| Tryptophan SCHEMBL325026 | 0.99 | KMT2A (0.78) | KMT2AKDM4EMAPTLMNATSHR | |
| Dl-Tryptophan SCHEMBL27561249 | 0.99 | KMT2A (0.78) | KMT2AKDM4EMAPTLMNATSHR | |
| Tryptophan SCHEMBL9449482 | 0.95 | KDM4E (0.73) | KMT2AKDM4EMAPTLMNATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 467 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024007778-A1 | USE OF PLASMA MOLECULAR MARKER KYNURENINE IN DETECTION OF EARLY HEART FAILURE | 上海交通大学医学院附属上海儿童医学中心 | 2024-01-11 | — | — | WO | claimed |
| WO-2023083323-A1 | A PEPTIDE AND THE SELECTION METHOD THEREOF | THE HONG KONG UNIVERSITY OF SCIENCE AND TECHNOLOGY (CN) | 2023-05-19 | — | — | WO | claimed |
| CN-115714027-A | Application of metabolic marker, parkinson disease diagnosis model and diagnosis device | 广东省中医院（广州中医药大学第二附属医院、广州中医药大学第二临床医学院、广东省中医药科学院） | 2023-02-24 | — | — | CN | claimed |
| CN-115327129-A | Application of plasma molecular marker kynurenine in early heart failure detection | 上海交通大学医学院附属上海儿童医学中心 | 2022-11-11 | — | — | CN | claimed |
| CN-112255335-B | Plasma metabolism marker for distinguishing benign ovarian tumor from malignant ovarian tumor and application thereof | 复旦大学 | 2022-06-17 | — | — | CN | claimed |
| EP-3177669-B1 | AMPHIPHILIC BLOCKCOPOLYMERS COMPRISING REDUCTION SENSITIVE BIODEGRADABLE POLYESTERAMIDES | DSM IP ASSETS BV (NL) | 2021-03-17 | — | — | EP | claimed |
| CN-112255335-A | Plasma metabolic marker for distinguishing benign ovarian tumor from malignant ovarian tumor and application thereof | 复旦大学 | 2021-01-22 | — | — | CN | claimed |
| WO-2018146484-A1 | SCREENING METHOD AND KIT TO DETECT RECEPTOR ACTIVATION | UNIVERSITY OF PORTSMOUTH HIGHER EDUCATION CORPORATION (GB) | 2018-08-16 | — | — | WO | claimed |
| EP-3177669-A1 | AMPHIPHILIC BLOCKCOPOLYMERS COMPRISING REDUCTION SENSITIVE BIODEGRADABLE POLYESTERAMIDES | DSM IP Assets B.V. (NL) | 2017-06-14 | — | — | EP | claimed |
| US-20160106715-A1 | METHODS TO INHIBIT INFECTION DURING WOUND HEALING WITH TOPICAL COMPOSITIONS INCLUDING AMINO ACIDS | PLUMB JOHN H (US) | 2016-04-21 | — | — | US | claimed |
| EP-0758843-A4 | MODIFIED AMINO ACIDS FOR DRUG DELIVERY | EMISPHERE TECH INC (US) | 1998-05-20 | — | — | EP | claimed |
| US-5686422-A | Synthetic inhibitors of mammalian collagenase | RESEARCH CORPORATION TECHNOLOGIES, INC. (US) | 1997-11-11 | — | — | US | claimed |
| US-5629020-A | Modified amino acids for drug delivery | EMISPHERE TECHNOLOGIES, INC. (US) | 1997-05-13 | — | — | US | claimed |
| EP-0758843-A1 | MODIFIED AMINO ACIDS FOR DRUG DELIVERY | Emisphere Technologies, Inc. (US) | 1997-02-26 | — | — | EP | claimed |
| EP-0696208-A4 | ORAL DRUG DELIVERY COMPOSITIONS AND METHODS | EMISPHERE TECH INC (US) | 1997-01-29 | — | — | EP | claimed |
| EP-0696208-A1 | ORAL DRUG DELIVERY COMPOSITIONS AND METHODS | Emisphere Technologies, Inc. (US) | 1996-02-14 | — | — | EP | claimed |
| WO-1995028838-A1 | MODIFIED AMINO ACIDS FOR DRUG DELIVERY | EMISPHERE TECHNOLOGIES, INC. (US) | 1995-11-02 | — | — | WO | claimed |
| WO-1994023767-A1 | ORAL DRUG DELIVERY COMPOSITIONS AND METHODS | EMISPHERE TECHNOLOGIES, INC. (US) | 1994-10-27 | — | — | WO | claimed |
| EP-0313380-B1 | Synthetic melanin aggregates | ADVANCED POLYMER SYSTEMS INC (US) | 1993-12-29 | — | — | EP | claimed |
| EP-0290269-A2 | Immunoassay methods and reagents and methods for producing the latter | CYBERFLUOR INC. (CA) | 1988-11-09 | — | — | EP | claimed |