Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 2/20 | 0.42 |
| ▸ | PPARG | P37231 | 4/20 | 0.39 |
| ▸ | PPARD | Q03181 | 4/20 | 0.39 |
| ▸ | PPARA | Q07869 | 4/20 | 0.39 |
| ▸ | TERT | O14746 | 3/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.39 |
| ▸ | FABP4 | P15090 | 3/20 | 0.39 |
| ▸ | F7 | P08709 | 3/20 | 0.39 |
| ▸ | F3 | P13726 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | BLM | P54132 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.39 |
| ▸ | DUSP3 | P51452 | 2/20 | 0.39 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.39 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.39 |
| ▸ | SIRT6 | Q8N6T7 | 2/20 | 0.39 |
| ▸ | PTPN7 | P35236 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10769612 | 1.00 | ALOX5 (0.42) | ALOX5PPARGPPARDPPARATERT | |
| SCHEMBL10359283 | 1.00 | ALOX5 (0.42) | ALOX5PPARGPPARDPPARATERT | |
| SCHEMBL10769610 | 1.00 | ALOX5 (0.42) | ALOX5PPARGPPARDPPARATERT | |
| SCHEMBL10359449 | 0.97 | ALOX5 (0.43) | ALOX5PPARGPPARDPPARATERT | |
| SCHEMBL10359450 | 0.97 | ALOX5 (0.43) | ALOX5PPARGPPARDPPARATERT | |
| SCHEMBL10359749 | 0.94 | ALOX5 (0.36) | ALOX5PPARGPPARDPPARATERT | |
| SCHEMBL10360121 | 0.94 | ALOX5 (0.36) | ALOX5PPARGPPARDPPARATERT | |
| SCHEMBL10765779 | 0.94 | ALOX5 (0.36) | ALOX5PPARGPPARDPPARATERT | |
| SCHEMBL10768129 | 0.94 | ALOX5 (0.36) | ALOX5PPARGPPARDPPARATERT | |
| SCHEMBL10360120 | 0.94 | ALOX5 (0.36) | ALOX5PPARGPPARDPPARATERT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0213547-B1 | CYCLOHEXANEALKANOIC ACIDS | MERRELL DOW PHARMACEUTICALS INC. (US) | 1990-12-27 | — | — | EP | disclosed |
| EP-0213547-A1 | Cyclohexanealkanoic acids | MERRELL DOW PHARMACEUTICALS INC. (US) | 1987-03-11 | — | — | EP | disclosed |
| US-4622422-A | FOR TREATMENT OF BRONCHIAL ASTHMA | MERRELL DOW PHARMACEUTICALS INC. (US) | 1986-11-11 | — | — | US | disclosed |