Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.32 |
| ▸ | BLM | P54132 | 1/20 | 0.32 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | THRB | P10828 | 1/20 | 0.30 |
| ▸ | RECQL | P46063 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ethyne SCHEMBL18186431 | 1.00 | LMNA (0.37) | LMNATSHRSLC6A2SLC6A4BLM | |
| SCHEMBL175982 | 0.94 | — | — | |
| SCHEMBL31299606 | 0.90 | LMNA (0.39) | LMNATSHRSLC6A2SLC6A4BLM | |
| SCHEMBL28788958 | 0.90 | LMNA (0.39) | LMNATSHRSLC6A2SLC6A4BLM | |
| Charcoal, Activated SCHEMBL8053844 | 0.90 | LMNA (0.39) | LMNATSHRSLC6A2SLC6A4BLM | |
| Potassium SCHEMBL31299607 | 0.90 | LMNA (0.39) | LMNATSHRSLC6A2SLC6A4BLM | |
| Lithium SCHEMBL31299622 | 0.90 | LMNA (0.39) | LMNATSHRSLC6A2SLC6A4BLM | |
| SCHEMBL28238346 | 0.90 | LMNA (0.39) | LMNATSHRSLC6A2SLC6A4BLM | |
| Boric Acid SCHEMBL28788886 | 0.85 | LMNA (0.35) | LMNATSHRSLC6A2SLC6A4BLM | |
| Acetic Acid SCHEMBL27696979 | 0.85 | FFAR3 (0.41) | LMNATSHRSLC6A2SLC6A4BLM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0198892-B1 | METHOD FOR PREPARING 1-HYDROXYVITAMIN D COMPOUNDS | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 1990-12-27 | — | — | EP | claimed |
| EP-0198892-A4 | METHOD FOR PREPARING 1-HYDROXYVITAMIN D COMPOUNDS. | WISCONSIN ALUMNI RES FOUND (US) | 1987-03-12 | — | — | EP | claimed |
| EP-0198892-A1 | METHOD FOR PREPARING 1-HYDROXYVITAMIN D COMPOUNDS. | WISCONSIN ALUMNI RES FOUND (US) | 1986-10-29 | — | — | EP | claimed |
| WO-1986002649-A1 | METHOD FOR PREPARING 1-HYDROXYVITAMIN D COMPOUNDS | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 1986-05-09 | — | — | WO | claimed |
| US-4555364-A | Method for preparing 1-hydroxyvitamin D compounds | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 1985-11-26 | — | — | US | claimed |