Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 7/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | APEX1 | P27695 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | ACHE | P22303 | 6/20 | 0.33 |
| ▸ | HCAR2 | Q8TDS4 | 3/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acrylonitrile SCHEMBL8964274 | 0.89 | TSHR (0.56) | TSHRHPGDALDH1A1CYP3A4ATM | |
| SCHEMBL29290397 | 0.88 | TSHR (0.65) | TSHRHPGDALDH1A1CYP3A4ATM | |
| Acrylonitrile SCHEMBL27884426 | 0.84 | TSHR (0.59) | TSHRHPGDALDH1A1CYP3A4ATM | |
| SCHEMBL9776629 | 0.84 | TSHR (0.67) | TSHRHPGDALDH1A1CYP3A4ATM | |
| Acrylic Acid Ethyl Ester SCHEMBL13276202 | 0.83 | TSHR (0.49) | TSHRHPGDALDH1A1CYP3A4ATM | |
| Acrylic Acid Ethyl Ester SCHEMBL13276142 | 0.83 | TSHR (0.49) | TSHRHPGDALDH1A1CYP3A4ATM | |
| Acrylonitrile SCHEMBL4005713 | 0.83 | TSHR (0.64) | TSHRHPGDALDH1A1ATMPOLB | |
| SCHEMBL8067773 | 0.83 | TSHR (0.58) | TSHRHPGDALDH1A1CYP3A4ATM | |
| Acrylonitrile SCHEMBL5365297 | 0.82 | TSHR (0.59) | TSHRHPGDALDH1A1CYP3A4ATM | |
| SCHEMBL5437346 | 0.81 | TSHR (0.67) | TSHRHPGDALDH1A1CYP3A4ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0392767-A2 | Thermoplastic acrylic elastomers | ROHM AND HAAS COMPANY (US) | 1990-10-17 | — | — | EP | disclosed |
| EP-0392766-A2 | Damping compositions | ROHM AND HAAS COMPANY (US) | 1990-10-17 | — | — | EP | disclosed |