Acrylonitrile

Acrylonitrile

SCHEMBL8964274

C=C(C)C(=O)OCCO.C=CC#N.C=CC(=O)OCCCC

nearest known ligand 0.56

Full drug profile on Sugi Atlas →

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
TSHR P16473 9/20 0.56
HPGD P15428 1/20 0.56
ALDH1A1 P00352 4/20 0.41
CYP3A4 P08684 1/20 0.41
ATM Q13315 1/20 0.41
THRB P10828 2/20 0.38
HCAR2 Q8TDS4 3/20 0.37
POLB P06746 1/20 0.35
APEX1 P27695 1/20 0.35
HTT P42858 1/20 0.35
TDP1 Q9NUW8 1/20 0.35
TP53 P04637 3/20 0.35
HIF1A Q16665 2/20 0.35
HSD17B10 Q99714 1/20 0.35
ACHE P22303 1/20 0.33
MAPT P10636 1/20 0.33
RAB9A P51151 1/20 0.33
NPSR1 Q6W5P4 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Acrylic Acid Ethyl Ester SCHEMBL13276202 0.93 TSHR (0.49) TSHRHPGDALDH1A1CYP3A4ATM
Acrylic Acid Ethyl Ester SCHEMBL13276142 0.93 TSHR (0.49) TSHRHPGDALDH1A1CYP3A4ATM
SCHEMBL10601730 0.92 TSHR (0.67) TSHRHPGDALDH1A1CYP3A4ATM
SCHEMBL10905162 0.92 TSHR (0.67) TSHRHPGDALDH1A1CYP3A4ATM
SCHEMBL5437346 0.92 TSHR (0.67) TSHRHPGDALDH1A1CYP3A4ATM
Acrylonitrile SCHEMBL26970011 0.91 TSHR (0.69) TSHRHPGDALDH1A1CYP3A4ATM
Acrylonitrile SCHEMBL27884426 0.90 TSHR (0.59) TSHRHPGDALDH1A1CYP3A4ATM
SCHEMBL10906110 0.89 TSHR (0.63) TSHRHPGDALDH1A1CYP3A4ATM
Acrylonitrile SCHEMBL10359604 0.89 TSHR (0.50) TSHRHPGDALDH1A1CYP3A4ATM
SCHEMBL9443466 0.88 TSHR (0.67) TSHRHPGDALDH1A1CYP3A4ATM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2519088-A1 CONDUCTIVE CONNECTION MATERIAL, ELECTRONIC COMPONENT PRODUCING METHOD, AND ELECTRONIC MEMBER AND ELECTRONIC COMPONENT WITH CONDUCTIVE CONNECTION MATERIAL Sumitomo Bakelite Co., Ltd. (JP) 2012-10-31 EP disclosed
US-20120261174-A1 CONDUCTIVE CONNECTING MATERIAL, METHOD FOR PRODUCING ELECTRONIC COMPONENT, ELECTRONIC MEMBER WITH CONDUCTIVE CONNECTING MATERIAL AND ELECTRONIC COMPONENT SUMITOMO BAKELITE CO., LTD. (JP) 2012-10-18 US disclosed
EP-0390527-B1 Toners for use in electrophotography and production thereof BANDO CHEMICAL IND (JP) 1996-02-21 EP disclosed
EP-0297839-B1 A process for producing toners for use in electrophotography BANDO CHEMICAL IND (JP) 1995-04-05 EP disclosed
US-5328795-A Suspension polymerization with color a monomer to form spheres BANDO CHEMICAL INDUSTRIES, LTD. (JP) 1994-07-12 US disclosed
EP-0390527-A2 Toners for use in electrophotography and production thereof BANDO CHEMICAL INDUSTRIES, LIMITED (JP) 1990-10-03 EP disclosed
US-4904560-A RADICAL POLYMERIZABLE MONOMER AND CARBON BLACK STIRRED WITH A PEROXIDE INITIATOR TO UNIFORMLY DISPERSE; ADDING AZOBISNITRILE TO POLYMERIZE BANDO CHEMICAL INDUSTRIES, LTD. (JP) 1990-02-27 US disclosed
EP-0297839-A2 A process for producing toners for use in electrophotography BANDO CHEMICAL INDUSTRIES, LIMITED (JP) 1989-01-04 EP disclosed