Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | CETP | P11597 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.40 |
| ▸ | CNR1 | P21554 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | FFAR1 | O14842 | 4/20 | 0.38 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.38 |
| ▸ | MMP1 | P03956 | 1/20 | 0.37 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10652565 | 0.87 | CETP (0.44) | TDP1KDM4EALDH1A1CETPLMNA | |
| SCHEMBL10346735 | 0.87 | CETP (0.44) | TDP1KDM4EALDH1A1CETPLMNA | |
| SCHEMBL10359644 | 0.85 | TDP1 (0.42) | TDP1KDM4EALDH1A1CETPLMNA | |
| SCHEMBL10346989 | 0.82 | ALDH1A1 (0.40) | TDP1KDM4EALDH1A1CETPLMNA | |
| SCHEMBL10346990 | 0.82 | ALDH1A1 (0.40) | TDP1KDM4EALDH1A1CETPLMNA | |
| SCHEMBL10346988 | 0.82 | ALDH1A1 (0.40) | TDP1KDM4EALDH1A1CETPLMNA | |
| SCHEMBL9559057 | 0.81 | KDM4E (0.46) | TDP1KDM4EALDH1A1CETPLMNA | |
| SCHEMBL10849876 | 0.79 | KDM4E (0.43) | TDP1KDM4EALDH1A1CETPLMNA | |
| SCHEMBL10532258 | 0.78 | NPC1 (0.44) | TDP1KDM4EALDH1A1CETPLMNA | |
| SCHEMBL10464786 | 0.78 | TDP1 (0.43) | TDP1KDM4EALDH1A1CETPLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0227369-B1 | INSECTICIDAL ALKENES | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1990-04-18 | — | — | EP | disclosed |
| US-4904677-A | Certain phenoxy- or benzyl substituted pyridylmethyloxy-alkenes having insecticidal properties | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1990-02-27 | — | — | US | disclosed |
| US-4812483-A | PESTICIDES, MITICIDES | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1989-03-14 | — | — | US | disclosed |
| EP-0227369-A1 | Insecticidal alkenes | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1987-07-01 | — | — | EP | disclosed |