Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGIR | P43119 | 2/20 | 0.49 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 4/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.38 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.38 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.38 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.38 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL10506008 | 0.99 | PTGIR (0.48) | PTGIRADRB3TP53SMN1; SMN2ALDH1A1 | |
| SCHEMBL10359077 | 0.91 | PTGIR (0.49) | PTGIRADRB3TP53SMN1; SMN2ALDH1A1 | |
| SCHEMBL9877935 | 0.90 | PTGIR (0.53) | PTGIRADRB3TP53SMN1; SMN2ALDH1A1 | |
| Hydrochloric Acid SCHEMBL9877187 | 0.90 | PTGIR (0.48) | PTGIRADRB3TP53SMN1; SMN2ALDH1A1 | |
| SCHEMBL9877283 | 0.86 | PTGIR (0.51) | PTGIRADRB3TP53SMN1; SMN2RAB9A | |
| SCHEMBL9877735 | 0.85 | PTGIR (0.48) | PTGIRADRB3TP53SMN1; SMN2ALDH1A1 | |
| Ipazilide SCHEMBL635854 | 0.84 | MAPK1 (0.55) | PTGIRTP53ALDH1A1KMT2AMAPK1 | |
| Hydrochloric Acid SCHEMBL9877683 | 0.84 | PTGIR (0.47) | PTGIRADRB3TP53ALDH1A1KMT2A | |
| SCHEMBL9878048 | 0.83 | TP53 (0.46) | PTGIRADRB3TP53ALDH1A1KMT2A | |
| Ipazilide SCHEMBL9877353 | 0.83 | MAPK1 (0.54) | PTGIRTP53ALDH1A1KMT2AMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0299407-B1 | 1H-PYRAZOLE-1-ALKANAMIDES AND PREPARATION USEFUL AS ANTIARRHYTHMIC AGENTS | STERLING DRUG INC. (US) | 1990-10-24 | — | — | EP | disclosed |