Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.36 |
| ▸ | ACHE | P22303 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.35 |
| ▸ | KIF11 | P52732 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1114876 | 0.80 | ALDH1A1 (0.50) | ALDH1A1TSHRTDP1HSP90AA1SMN1; SMN2 | |
| SCHEMBL2927687 | 0.80 | ALDH1A1 (0.62) | ALDH1A1TSHRHTTMAPTKMT2A | |
| SCHEMBL14850480 | 0.80 | ALDH1A1 (0.62) | ALDH1A1TSHRHTTMAPTKMT2A | |
| SCHEMBL2732382 | 0.78 | ALDH1A1 (0.41) | ALDH1A1TSHRTDP1HTTMAPT | |
| SCHEMBL11437771 | 0.78 | ALDH1A1 (0.52) | ALDH1A1TSHRTDP1HSP90AA1HTT | |
| SCHEMBL1275971 | 0.74 | ALDH1A1 (0.44) | ALDH1A1TSHRTDP1HSP90AA1HTT | |
| SCHEMBL6710111 | 0.74 | ESR1 (0.39) | ALDH1A1TSHRHTTMAPTSMN1; SMN2 | |
| SCHEMBL7174365 | 0.74 | ALDH1A1 (0.37) | ALDH1A1TSHRHSP90AA1HTTMAPT | |
| SCHEMBL677566 | 0.73 | ALDH1A1 (0.45) | ALDH1A1TSHRTDP1HSP90AA1HTT | |
| SCHEMBL1077646 | 0.73 | ALDH1A1 (0.46) | ALDH1A1TSHRTDP1HSP90AA1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8377856-B2 | Extended drain diesel lubricant formulations | AFTON CHEMICAL CORPORATION (US) | 2013-02-19 | — | — | US | claimed |
| US-20110003722-A1 | EXTENDED DRAIN DIESEL LUBRICANT FORMULATIONS | AFTON CHEMICAL CORPORATION (US) | 2011-01-06 | — | — | US | claimed |
| US-20100292112-A1 | EXTENDED DRAIN DIESEL LUBRICANT FORMULATIONS | AFTON CHEMICAL CORPORATION (US) | 2010-11-18 | — | — | US | claimed |
| US-20100292112-A1 | EXTENDED DRAIN DIESEL LUBRICANT FORMULATIONS | AFTON CHEMICAL CORPORATION (US) | 2010-11-18 | — | — | US | disclosed |