Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 1/20 | 0.45 |
| ▸ | HTR2A | P28223 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.39 |
| ▸ | DRD2 | P14416 | 1/20 | 0.39 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.39 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
| ▸ | HTR2C | P28335 | 1/20 | 0.39 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.39 |
| ▸ | HRH1 | P35367 | 1/20 | 0.39 |
| ▸ | DRD3 | P35462 | 1/20 | 0.39 |
| ▸ | THPO | P40225 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31185871 | 1.00 | HTR6 (0.45) | HTR6HTR2AKDM4ELMNATP53 | |
| SCHEMBL30679045 | 1.00 | HTR6 (0.45) | HTR6HTR2AKDM4ELMNATP53 | |
| SCHEMBL5033500 | 1.00 | HTR6 (0.45) | HTR6HTR2AKDM4ELMNATP53 | |
| SCHEMBL6055948 | 1.00 | HTR6 (0.45) | HTR6HTR2AKDM4ELMNATP53 | |
| SCHEMBL6674209 | 1.00 | HTR6 (0.45) | HTR6HTR2AKDM4ELMNATP53 | |
| SCHEMBL27082282 | 1.00 | HTR6 (0.45) | HTR6HTR2AKDM4ELMNATP53 | |
| SCHEMBL29546963 | 0.98 | HTR6 (0.46) | HTR6HTR2AKDM4ELMNATP53 | |
| SCHEMBL2641527 | 0.98 | HTR6 (0.46) | HTR6HTR2AKDM4ELMNATP53 | |
| SCHEMBL1028711 | 0.93 | HTR6 (0.47) | HTR6HTR2AKDM4ELMNATP53 | |
| SCHEMBL6675371 | 0.91 | HTR6 (0.51) | HTR6HTR2AKDM4ELMNATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0213547-B1 | CYCLOHEXANEALKANOIC ACIDS | MERRELL DOW PHARMACEUTICALS INC. (US) | 1990-12-27 | — | — | EP | disclosed |