Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | APAF1 | O14727 | 1/20 | 0.36 |
| ▸ | FABP4 | P15090 | 1/20 | 0.35 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.35 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.34 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.34 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10361138 | 0.86 | MAPT (0.39) | MAPTGAACYP1A2CYP2C9PKM | |
| SCHEMBL10361114 | 0.85 | MAPT (0.39) | MAPTGAACYP1A2CYP2C9PKM | |
| SCHEMBL10360329 | 0.83 | TDP1 (0.38) | GAACYP1A2CYP2C9PKMCYP2C19 | |
| SCHEMBL10361312 | 0.82 | MAPT (0.56) | MAPTGAACYP1A2CYP2C9PKM | |
| SCHEMBL10361364 | 0.78 | MAPT (0.42) | MAPTKMT2AALDH1A1NOTUMNPC1 | |
| SCHEMBL10361082 | 0.76 | TDP1 (0.40) | MAPTGAACYP1A2CYP2C9PKM | |
| SCHEMBL10361131 | 0.76 | TDP1 (0.38) | GAACYP1A2CYP2C9PKMCYP2C19 | |
| SCHEMBL10361111 | 0.75 | TSHR (0.45) | MAPTALDH1A1NOTUMSMN1; SMN2 | |
| SCHEMBL10360399 | 0.75 | MAPT (0.44) | MAPTGAACYP1A2CYP2C9PKM | |
| SCHEMBL10360281 | 0.74 | GRIN1 (0.43) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0179217-A2 | Process for the preparation of 2-hydroxy-5,6,7,8-tetrahydrocarbazol and its salts, and their uses | HOECHST AKTIENGESELLSCHAFT (DE) | 1986-04-30 | — | — | EP | claimed |
| US-4931083-A | Plant growth regulating triazoles | ELI LILLY AND COMPANY (US) | 1990-06-05 | — | — | US | disclosed |
| EP-0227284-A1 | Plant Growth regulating triazoles | ELI LILLY AND COMPANY (US) | 1987-07-01 | — | — | EP | disclosed |
| EP-0179217-A3 | PROCESS FOR THE PREPARATION OF 2-HYDROXY-5,6,7,8-TETRAHYDROCARBAZOL AND ITS SALTS, AND THEIR USES | HOECHST AKTIENGESELLSCHAFT (DE) | 1987-06-03 | — | — | EP | disclosed |
| EP-0179217-A3 | PROCESS FOR THE PREPARATION OF 2-HYDROXY-5,6,7,8-TETRAHYDROCARBAZOL AND ITS SALTS, AND THEIR USES | HOECHST AKTIENGESELLSCHAFT (DE) | 1987-06-03 | — | — | EP | disclosed |
| EP-0179217-A2 | Process for the preparation of 2-hydroxy-5,6,7,8-tetrahydrocarbazol and its salts, and their uses | HOECHST AKTIENGESELLSCHAFT (DE) | 1986-04-30 | — | — | EP | disclosed |
| EP-0179217-A2 | Process for the preparation of 2-hydroxy-5,6,7,8-tetrahydrocarbazol and its salts, and their uses | HOECHST AKTIENGESELLSCHAFT (DE) | 1986-04-30 | — | — | EP | disclosed |
| EP-0179217-A2 | Process for the preparation of 2-hydroxy-5,6,7,8-tetrahydrocarbazol and its salts, and their uses | HOECHST AKTIENGESELLSCHAFT (DE) | 1986-04-30 | — | — | EP | disclosed |