Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | HTR2A | P28223 | 1/20 | 0.45 |
| ▸ | HTR2C | P28335 | 1/20 | 0.45 |
| ▸ | HTR2B | P41595 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | CNR2 | P34972 | 3/20 | 0.40 |
| ▸ | CNR1 | P21554 | 3/20 | 0.40 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.40 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.39 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | MAP4K4 | O95819 | 2/20 | 0.38 |
| ▸ | RPA1 | P27694 | 1/20 | 0.38 |
| ▸ | PPARG | P37231 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10361135 | 0.88 | CNR1 (0.41) | TSHRLMNACNR2CNR1MAPT | |
| SCHEMBL10360709 | 0.87 | CNR2 (0.39) | LMNACNR2CNR1NOTUM | |
| SCHEMBL10360670 | 0.86 | GABRA2 (0.44) | CNR2CNR1MAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL10361114 | 0.85 | MAPT (0.39) | TSHRHTR2AHTR2CHTR2BNOTUM | |
| SCHEMBL10360696 | 0.82 | MAPT (0.43) | TSHRHTR2AHTR2CHTR2BNOTUM | |
| SCHEMBL10360682 | 0.81 | MAPT (0.43) | TSHRHTR2AHTR2CHTR2BNOTUM | |
| SCHEMBL10360745 | 0.81 | TSHR (0.40) | TSHRHTR2AHTR2CHTR2BNOTUM | |
| SCHEMBL10361327 | 0.79 | NOTUM (0.55) | TSHRHTR2AHTR2CHTR2BCNR2 | |
| SCHEMBL10360329 | 0.76 | TDP1 (0.38) | PPARGALDH1A1 | |
| SCHEMBL10361131 | 0.76 | TDP1 (0.38) | PTGDRMAP4K4ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4931083-A | Plant growth regulating triazoles | ELI LILLY AND COMPANY (US) | 1990-06-05 | — | — | US | disclosed |
| EP-0227284-A1 | Plant Growth regulating triazoles | ELI LILLY AND COMPANY (US) | 1987-07-01 | — | — | EP | disclosed |