Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 6/20 | 0.46 |
| ▸ | F2 | P00734 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 4/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | PARP1 | P09874 | 1/20 | 0.39 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.39 |
| ▸ | PARP3 | Q9Y6F1 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | FLT3 | P36888 | 2/20 | 0.36 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.35 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10360356 | 0.80 | NOTUM (0.40) | NOTUMNPSR1L3MBTL1MAPTALDH1A1 | |
| SCHEMBL10361314 | 0.80 | ALDH1A1 (0.43) | NOTUMF2RAB9AKDM4EMAPT | |
| SCHEMBL10360312 | 0.79 | NOTUM (0.56) | NOTUMRAB9ANPC1SMN1; SMN2 | |
| SCHEMBL4857635 | 0.79 | MAPT (0.47) | NOTUMNPSR1L3MBTL1RAB9AKDM4E | |
| SCHEMBL10361336 | 0.78 | NOTUM (0.47) | NOTUML3MBTL1KDM4EMAPTALDH1A1 | |
| SCHEMBL2360137 | 0.76 | NOTUM (0.46) | NOTUMF2NPSR1L3MBTL1RAB9A | |
| SCHEMBL16202009 | 0.76 | NOTUM (0.46) | NOTUMF2NPSR1L3MBTL1RAB9A | |
| SCHEMBL19402280 | 0.76 | NOTUM (0.47) | NOTUMF2NPSR1L3MBTL1RAB9A | |
| SCHEMBL6132524 | 0.76 | CYP1A2 (0.47) | RAB9AKDM4EMAPTNPC1ALDH1A1 | |
| SCHEMBL10360310 | 0.76 | NOTUM (0.44) | NOTUMCYP11B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4931083-A | Plant growth regulating triazoles | ELI LILLY AND COMPANY (US) | 1990-06-05 | — | — | US | disclosed |
| EP-0227284-A1 | Plant Growth regulating triazoles | ELI LILLY AND COMPANY (US) | 1987-07-01 | — | — | EP | disclosed |