Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | CDK1 | P06493 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | NLRP3 | Q96P20 | 4/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10362436 | 1.00 | GAA (0.50) | GAACDK1CYP1A2MAPTTP53 | |
| SCHEMBL10361241 | 0.94 | GAA (0.44) | GAACDK1CYP1A2MAPTNLRP3 | |
| SCHEMBL10361242 | 0.94 | GAA (0.44) | GAACDK1CYP1A2MAPTNLRP3 | |
| SCHEMBL1535829 | 0.82 | GAA (0.53) | GAACDK1CYP1A2MAPTTP53 | |
| SCHEMBL116670 | 0.82 | GAA (0.53) | GAACDK1CYP1A2MAPTTP53 | |
| SCHEMBL9661255 | 0.82 | GAA (0.53) | GAACDK1CYP1A2MAPTTP53 | |
| SCHEMBL6053633 | 0.80 | GAA (0.54) | GAACDK1CYP1A2MAPTTP53 | |
| SCHEMBL4459068 | 0.80 | GAA (0.54) | GAACDK1CYP1A2MAPTTP53 | |
| SCHEMBL9660372 | 0.79 | GAA (0.50) | GAACDK1CYP1A2MAPTTP53 | |
| SCHEMBL8845296 | 0.78 | GAA (0.49) | GAACDK1CYP1A2MAPTTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0187489-B1 | HERBICIDAL SULFONAMIDES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1990-12-12 | — | — | EP | disclosed |
| US-4822403-A | Herbicidal sulfonamides | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1989-04-18 | — | — | US | disclosed |
| EP-0187489-A1 | Herbicidal sulfonamides | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1986-07-16 | — | — | EP | disclosed |