Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | CDK1 | P06493 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL116670 | 0.88 | GAA (0.53) | GAACDK1CYP1A2TP53GLA | |
| SCHEMBL9661255 | 0.88 | GAA (0.53) | GAACDK1CYP1A2TP53GLA | |
| SCHEMBL1535829 | 0.88 | GAA (0.53) | GAACDK1CYP1A2TP53GLA | |
| Pyrazosulfuron Ethyl SCHEMBL22006 | 0.88 | GAA (0.48) | GAACDK1CYP1A2TP53GLA | |
| Pyrazosulfuron Ethyl SCHEMBL15524983 | 0.87 | GAA (0.47) | GAACDK1CYP1A2TP53GLA | |
| Pyrazosulfuron Ethyl SCHEMBL15513045 | 0.87 | GAA (0.47) | GAACDK1CYP1A2TP53GLA | |
| SCHEMBL9661254 | 0.86 | GAA (0.48) | GAACDK1CYP1A2TP53GLA | |
| Pyrazosulfuron Ethyl SCHEMBL369569 | 0.84 | GAA (0.45) | GAACDK1CYP1A2TP53GLA | |
| Pyrazosulfuron Ethyl SCHEMBL2440654 | 0.84 | GAA (0.45) | GAACDK1CYP1A2TP53GLA | |
| SCHEMBL9195352 | 0.83 | GAA (0.44) | GAACDK1MAPTKMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0245058-B1 | HERBICIDAL HETEROCYCLIC SULFONAMIDES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1992-03-18 | — | — | EP | claimed |
| US-4906278-A | Herbicidal heterocyclic sulfonamides | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1990-03-06 | — | — | US | claimed |
| EP-0245058-A2 | Herbicidal heterocyclic sulfonamides | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1987-11-11 | — | — | EP | claimed |
| EP-0245058-B1 | HERBICIDAL HETEROCYCLIC SULFONAMIDES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1992-03-18 | — | — | EP | disclosed |
| US-5011527-A | Herbicidal heterocyclic sulfonamides | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1991-04-30 | — | — | US | disclosed |
| US-4906278-A | Herbicidal heterocyclic sulfonamides | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1990-03-06 | — | — | US | disclosed |
| US-4778512-A | Herbicidal heterocyclic sulfonamides | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1988-10-18 | — | — | US | disclosed |
| EP-0245058-A2 | Herbicidal heterocyclic sulfonamides | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1987-11-11 | — | — | EP | disclosed |