Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TGM2 | P21980 | 9/20 | 0.44 |
| ▸ | ITK | Q08881 | 1/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.37 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.37 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.37 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | TYR | P14679 | 1/20 | 0.36 |
| ▸ | IDO1 | P14902 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10808081 | 0.95 | TGM2 (0.47) | TGM2ITKHDAC3HDAC1HDAC2 | |
| SCHEMBL10806137 | 0.90 | TGM2 (0.43) | TGM2ITKHDAC3HDAC1HDAC2 | |
| SCHEMBL10804531 | 0.84 | TGM2 (0.52) | TGM2ITKZDHHC20ZDHHC2GAA | |
| SCHEMBL10806368 | 0.83 | TGM2 (0.47) | TGM2ITKZDHHC20ZDHHC2GAA | |
| SCHEMBL10363161 | 0.80 | TGM2 (0.51) | TGM2ITKHDAC3HDAC1HDAC2 | |
| SCHEMBL10364770 | 0.80 | TGM2 (0.43) | TGM2ITKKMT2A | |
| SCHEMBL10803446 | 0.79 | TGM2 (0.56) | TGM2ITKZDHHC20ZDHHC2GAA | |
| SCHEMBL10807055 | 0.79 | TGM2 (0.49) | TGM2ITKZDHHC20ZDHHC2GAA | |
| SCHEMBL10816283 | 0.77 | TGM2 (0.47) | TGM2ITK | |
| SCHEMBL10363054 | 0.77 | KMT2A (0.54) | TGM2ITKKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0155177-B1 | UNSATURATED CYCLIC AMIDO-SUBSTITUTED ETHER COMPOUNDS AND PREPARATION PROCESS THEREOF | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1990-10-31 | — | — | EP | disclosed |
| US-4649219-A | CROSSLINKERS, ADHESIVES, PAINTS | MITSUI TOATSU CHEMICALS, INCORPORATED (JP) | 1987-03-10 | — | — | US | disclosed |