Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 5/20 | 0.66 |
| ▸ | TTR | P02766 | 3/20 | 0.66 |
| ▸ | CXCL8 | P10145 | 3/20 | 0.66 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.66 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.66 |
| ▸ | UGT1A9 | O60656 | 1/20 | 0.66 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.66 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.66 |
| ▸ | MT-CO2 | P00403 | 1/20 | 0.66 |
| ▸ | ALB | P02768 | 1/20 | 0.66 |
| ▸ | UGT1A6 | P19224 | 1/20 | 0.66 |
| ▸ | UGT1A1 | P22309 | 1/20 | 0.66 |
| ▸ | CXCR1 | P25024 | 1/20 | 0.66 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.66 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.66 |
| ▸ | NR1I3 | Q14994 | 1/20 | 0.66 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.66 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.66 |
| ▸ | UGT1A7 | Q9HAW7 | 1/20 | 0.66 |
| ▸ | UGT1A10 | Q9HAW8 | 1/20 | 0.66 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10364090 | 1.00 | PTGS2 (0.66) | PTGS2TTRCXCL8PTGS1AKR1B10 | |
| SCHEMBL10364087 | 1.00 | PTGS2 (0.66) | PTGS2TTRCXCL8PTGS1AKR1B10 | |
| SCHEMBL10364298 | 0.91 | PTGS2 (0.60) | PTGS2TTRCXCL8PTGS1AKR1B10 | |
| SCHEMBL11191782 | 0.89 | PTGS2 (0.64) | PTGS2TTRCXCL8PTGS1AKR1B10 | |
| SCHEMBL11191788 | 0.89 | PTGS2 (0.64) | PTGS2TTRCXCL8PTGS1AKR1B10 | |
| SCHEMBL11187261 | 0.88 | PTGS2 (0.63) | PTGS2TTRCXCL8PTGS1AKR1B10 | |
| SCHEMBL11187242 | 0.88 | PTGS2 (0.63) | PTGS2TTRCXCL8PTGS1AKR1B10 | |
| SCHEMBL11198201 | 0.88 | PTGS2 (0.62) | PTGS2TTRCXCL8PTGS1AKR1B10 | |
| SCHEMBL11187302 | 0.87 | PTGS2 (0.61) | PTGS2TTRCXCL8PTGS1AKR1B10 | |
| SCHEMBL11187272 | 0.84 | PTGS2 (0.57) | PTGS2TTRCXCL8PTGS1AKR1B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0253293-B1 | GUANIDINIUM SALTS OF ASPARTIC ACID | CIBA-GEIGY AG (CH) | 1990-02-28 | — | — | EP | claimed |
| US-4250192-A | ANTIINFLAMMATORY AGENTS | CIBA-GEIGY CORPORATION (US) | 1981-02-10 | — | — | US | claimed |
| US-4959394-A | ANTIINFLAMMATORY AGENTS, ANALGESICS, TASTE, WATER SOLUBILITY | CIBA-GEIGY CORPORATION (US) | 1990-09-25 | — | — | US | disclosed |
| US-4959394-A | ANTIINFLAMMATORY AGENTS, ANALGESICS, TASTE, WATER SOLUBILITY | CIBA-GEIGY CORPORATION (US) | 1990-09-25 | — | — | US | disclosed |
| EP-0253293-B1 | GUANIDINIUM SALTS OF ASPARTIC ACID | CIBA-GEIGY AG (CH) | 1990-02-28 | — | — | EP | disclosed |
| EP-0253293-B1 | GUANIDINIUM SALTS OF ASPARTIC ACID | CIBA-GEIGY AG (CH) | 1990-02-28 | — | — | EP | disclosed |
| EP-0253293-A1 | Guanidinium salts of aspartic acid | CIBA-GEIGY AG (CH) | 1988-01-20 | — | — | EP | disclosed |
| US-4421765-A | ANTIINFLAMMATORY AGENTS | CIBA-GEIGY CORPORATION (US) | 1983-12-20 | — | — | US | disclosed |
| US-4420490-A | ANTIINFLAMMATORY | CIBA-GEIGY CORPORATION (US) | 1983-12-13 | — | — | US | disclosed |
| US-4346105-A | ANTIINFLAMMATORY AGENTS | CIBA-GEIGY CORPORATION (US) | 1982-08-24 | — | — | US | disclosed |
| US-4346104-A | ANTIINFLAMMATORY | CIBA-GEIGY CORPORATION (US) | 1982-08-24 | — | — | US | disclosed |
| US-4322436-A | ANTIINFLAMMATORY AGENTS | CIBA-GEIGY CORPORATION (US) | 1982-03-30 | — | — | US | disclosed |
| US-4250192-A | ANTIINFLAMMATORY AGENTS | CIBA-GEIGY CORPORATION (US) | 1981-02-10 | — | — | US | disclosed |