Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 1/20 | 0.55 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | TGM2 | P21980 | 2/20 | 0.53 |
| ▸ | NPC1 | O15118 | 2/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.49 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10808817 | 0.92 | ZDHHC20 (0.51) | SMN1; SMN2TGM2NPC1RAB9AALDH1A1 | |
| SCHEMBL10805451 | 0.90 | ZDHHC2 (0.63) | TGM2NPC1RAB9AZDHHC20ZDHHC2 | |
| SCHEMBL10363985 | 0.88 | ZDHHC20 (0.49) | MTNR1AMTNR1BKMT2ASMN1; SMN2TGM2 | |
| SCHEMBL10807201 | 0.88 | NPC1 (0.57) | KMT2ATGM2NPC1RAB9AALDH1A1 | |
| SCHEMBL10364025 | 0.88 | HPGD (0.57) | KMT2ASMN1; SMN2TGM2NPC1ALDH1A1 | |
| SCHEMBL10806934 | 0.88 | ZDHHC2 (0.66) | ZDHHC20ZDHHC2 | |
| SCHEMBL10806063 | 0.87 | MAPT (0.60) | MTNR1AMTNR1BKMT2ASMN1; SMN2NPC1 | |
| SCHEMBL10808118 | 0.87 | ZDHHC2 (0.69) | TGM2ZDHHC20ZDHHC2 | |
| SCHEMBL10806715 | 0.87 | ZDHHC2 (0.69) | TGM2ZDHHC20ZDHHC2 | |
| SCHEMBL10806059 | 0.87 | ZDHHC2 (0.69) | TGM2ZDHHC20ZDHHC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0155177-B1 | UNSATURATED CYCLIC AMIDO-SUBSTITUTED ETHER COMPOUNDS AND PREPARATION PROCESS THEREOF | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1990-10-31 | — | — | EP | disclosed |
| US-4649219-A | CROSSLINKERS, ADHESIVES, PAINTS | MITSUI TOATSU CHEMICALS, INCORPORATED (JP) | 1987-03-10 | — | — | US | disclosed |
| EP-0155177-A2 | Unsaturated cyclic amido-substituted ether compounds and preparation process thereof | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1985-09-18 | — | — | EP | disclosed |