Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ANPEP | P15144 | 6/20 | 0.61 |
| ▸ | CA12 | O43570 | 2/20 | 0.54 |
| ▸ | CA1 | P00915 | 2/20 | 0.54 |
| ▸ | CA2 | P00918 | 2/20 | 0.54 |
| ▸ | CA9 | Q16790 | 2/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL74870 | 0.81 | ANPEP (0.81) | ANPEPCA12CA1CA2CA9 | |
| SCHEMBL74871 | 0.81 | ANPEP (0.81) | ANPEPCA12CA1CA2CA9 | |
| SCHEMBL10964500 | 0.80 | KDM4E (0.70) | ANPEPCA12CA1CA2CA9 | |
| SCHEMBL10964506 | 0.80 | KDM4E (0.70) | ANPEPCA12CA1CA2CA9 | |
| SCHEMBL75067 | 0.78 | POLB (0.60) | ANPEPCA12CA1CA2CA9 | |
| SCHEMBL75068 | 0.78 | POLB (0.60) | ANPEPCA12CA1CA2CA9 | |
| SCHEMBL10748636 | 0.77 | GAA (0.55) | ANPEPHTT | |
| SCHEMBL75549 | 0.77 | ANPEP (0.58) | ANPEPCA12CA1CA2CA9 | |
| SCHEMBL75550 | 0.77 | ANPEP (0.58) | ANPEPCA12CA1CA2CA9 | |
| SCHEMBL74974 | 0.76 | ANPEP (0.62) | ANPEPCA12CA1CA2CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0147211-B1 | 4H-3,1-BENZOXAZIN-4-ONES AND RELATED COMPOUNDS, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM, AND PROCESSES FOR THEIR PREPARATION | SYNTEX (U.S.A.) INC. (US) | 1990-09-12 | — | — | EP | disclosed |
| US-4657893-A | ANTIINFLAMMATORY AGENTS | SYNTEX (U.S.A.) INC. (US) | 1987-04-14 | — | — | US | disclosed |
| EP-0147211-A2 | 4H-3,1-benzoxazin-4-ones and related compounds, pharmaceutical compositions containing them, and processes for their preparation | SYNTEX (U.S.A.) INC. (US) | 1985-07-03 | — | — | EP | disclosed |