Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 1/20 | 0.48 |
| ▸ | PAOX | Q6QHF9 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | S1PR2 | O95136 | 5/20 | 0.39 |
| ▸ | S1PR4 | O95977 | 5/20 | 0.39 |
| ▸ | S1PR1 | P21453 | 5/20 | 0.39 |
| ▸ | S1PR3 | Q99500 | 5/20 | 0.39 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10363416 | 1.00 | EPHX1 (0.48) | EPHX1PAOXALDH1A1TSHRMAPT | |
| SCHEMBL10363927 | 0.97 | PAOX (0.46) | EPHX1PAOXALDH1A1TSHRMAPT | |
| SCHEMBL9248205 | 0.92 | — | — | |
| SCHEMBL10365351 | 0.90 | EPHX1 (0.48) | EPHX1PAOXALDH1A1TSHRMAPT | |
| SCHEMBL10363430 | 0.90 | EPHX1 (0.48) | EPHX1PAOXALDH1A1TSHRMAPT | |
| SCHEMBL10363448 | 0.90 | EPHX1 (0.48) | EPHX1PAOXALDH1A1TSHRMAPT | |
| SCHEMBL10364478 | 0.90 | EPHX1 (0.48) | EPHX1PAOXALDH1A1TSHRMAPT | |
| SCHEMBL10365483 | 0.90 | EPHX1 (0.48) | EPHX1PAOXALDH1A1TSHRMAPT | |
| SCHEMBL10365344 | 0.90 | EPHX1 (0.48) | EPHX1PAOXALDH1A1TSHRMAPT | |
| SCHEMBL10365435 | 0.90 | EPHX1 (0.48) | EPHX1PAOXALDH1A1TSHRMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4918107-A | HYDROXYPHENYLACETYL-L-ASPARAGINYL COMPOUNDS | TSUMURA & CO. (JP) | 1990-04-17 | — | — | US | disclosed |