Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
| ▸ | GBA1 | P04062 | 1/20 | 0.40 |
| ▸ | IDO1 | P14902 | 1/20 | 0.40 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6398540 | 1.00 | TDP1 (0.43) | TDP1ATMALDH1A1MAPTHPGD | |
| SCHEMBL8759638 | 1.00 | TDP1 (0.43) | TDP1ATMALDH1A1MAPTHPGD | |
| SCHEMBL10390103 | 0.91 | TDP1 (0.42) | TDP1ATMALDH1A1MAPTHPGD | |
| SCHEMBL10390568 | 0.90 | TDP1 (0.41) | TDP1ATMALDH1A1MAPTHPGD | |
| SCHEMBL7811546 | 0.90 | RAB9A (0.43) | TDP1ATMALDH1A1MAPTHPGD | |
| SCHEMBL10370030 | 0.88 | RAB9A (0.42) | TDP1ATMALDH1A1MAPTHPGD | |
| SCHEMBL9366831 | 0.87 | SPHK1 (0.44) | TDP1ATMALDH1A1MAPTHPGD | |
| SCHEMBL9518914 | 0.87 | TDP1 (0.40) | TDP1ATMALDH1A1MAPTHPGD | |
| SCHEMBL10370916 | 0.87 | RAB9A (0.42) | TDP1ATMALDH1A1MAPTHPGD | |
| SCHEMBL10363296 | 0.87 | MAOB (0.42) | TDP1ATMALDH1A1MAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0186525-B1 | CARBAPENEM COMPOUNDS, THEIR PREPARATION AND USE | SANKYO COMPANY LIMITED (JP) | 1990-04-04 | — | — | EP | disclosed |
| US-4740507-A | Carbapenem compounds and use | SANKYO COMPANY LIMITED (JP) | 1988-04-26 | — | — | US | disclosed |
| EP-0186525-A1 | Carbapenem compounds, their preparation and use | SANKYO COMPANY LIMITED (JP) | 1986-07-02 | — | — | EP | disclosed |