Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSC | P53634 | 3/20 | 0.59 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.54 |
| ▸ | REN | P00797 | 1/20 | 0.52 |
| ▸ | MME | P08473 | 2/20 | 0.51 |
| ▸ | EED | O75530 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | PSMB5 | P28074 | 2/20 | 0.49 |
| ▸ | LTA4H | P09960 | 1/20 | 0.49 |
| ▸ | ACE | P12821 | 1/20 | 0.49 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29958630 | 0.95 | REN (0.58) | CTSCRENMMEEEDPSMB5 | |
| SCHEMBL30052854 | 0.95 | CTSC (0.56) | CTSCLMNATDP1RENMME | |
| SCHEMBL28122660 | 0.92 | CTSC (0.68) | CTSCLMNATDP1MMEACE | |
| SCHEMBL21808154 | 0.92 | CTSC (0.68) | CTSCLMNATDP1MMEACE | |
| SCHEMBL11187709 | 0.92 | CTSC (0.68) | CTSCLMNATDP1MMEACE | |
| SCHEMBL28122659 | 0.92 | CTSC (0.68) | CTSCLMNATDP1MMEACE | |
| SCHEMBL601567 | 0.92 | CTSC (0.68) | CTSCLMNATDP1MMEACE | |
| SCHEMBL31026629 | 0.92 | CTSC (0.68) | CTSCLMNATDP1MMEACE | |
| SCHEMBL601566 | 0.92 | CTSC (0.68) | CTSCLMNATDP1MMEACE | |
| SCHEMBL3008134 | 0.92 | CTSC (0.68) | CTSCLMNATDP1MMEACE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0147211-B1 | 4H-3,1-BENZOXAZIN-4-ONES AND RELATED COMPOUNDS, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM, AND PROCESSES FOR THEIR PREPARATION | SYNTEX (U.S.A.) INC. (US) | 1990-09-12 | — | — | EP | disclosed |
| US-4657893-A | ANTIINFLAMMATORY AGENTS | SYNTEX (U.S.A.) INC. (US) | 1987-04-14 | — | — | US | disclosed |
| EP-0147211-A2 | 4H-3,1-benzoxazin-4-ones and related compounds, pharmaceutical compositions containing them, and processes for their preparation | SYNTEX (U.S.A.) INC. (US) | 1985-07-03 | — | — | EP | disclosed |