Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AXL | P30530 | 1/20 | 0.37 |
| ▸ | MERTK | Q12866 | 1/20 | 0.37 |
| ▸ | REN | P00797 | 2/20 | 0.34 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.34 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.33 |
| ▸ | RORC | P51449 | 5/20 | 0.33 |
| ▸ | GPR119 | Q8TDV5 | 4/20 | 0.32 |
| ▸ | BACE1 | P56817 | 1/20 | 0.32 |
| ▸ | HRH2 | P25021 | 2/20 | 0.31 |
| ▸ | HRH1 | P35367 | 2/20 | 0.31 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.31 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1040276 | 0.91 | REN (0.36) | RENRORC | |
| SCHEMBL1040275 | 0.91 | REN (0.36) | RENRORC | |
| SCHEMBL1039349 | 0.91 | AXL (0.39) | AXLMERTKRENPDE4BPRMT5 | |
| SCHEMBL1039408 | 0.91 | AXL (0.39) | AXLMERTKRENPDE4BRORC | |
| SCHEMBL3905694 | 0.90 | REN (0.36) | RENRORC | |
| SCHEMBL3905699 | 0.90 | REN (0.36) | RENRORC | |
| SCHEMBL4583243 | 0.90 | REN (0.36) | RENRORCHRH2HRH1 | |
| SCHEMBL4583244 | 0.90 | REN (0.36) | RENRORCHRH2HRH1 | |
| SCHEMBL4583214 | 0.89 | REN (0.33) | RENRORC | |
| SCHEMBL4583210 | 0.89 | REN (0.33) | RENRORC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2049514-B1 | NITRATE ESTERS OF PIPERIDINES | NOVARTIS AG (CH) | 2011-01-26 | — | — | EP | disclosed |