Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.49 |
| ▸ | PPP1CA | P62136 | 1/20 | 0.48 |
| ▸ | ALKBH1 | Q13686 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 3/20 | 0.46 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.46 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3076270 | 0.87 | MAPT (0.59) | HTTKMT2AL3MBTL1NPC1RAB9A | |
| SCHEMBL3376392 | 0.85 | HTT (0.67) | HTTKMT2ANPC1RAB9AATM | |
| SCHEMBL6052435 | 0.85 | KMT2A (0.64) | HTTKMT2AL3MBTL1NPC1RAB9A | |
| SCHEMBL10364105 | 0.82 | KMT2A (0.55) | HTTKMT2AL3MBTL1NPC1RAB9A | |
| SCHEMBL10340538 | 0.82 | HTT (0.51) | HTTKMT2AL3MBTL1NPC1RAB9A | |
| SCHEMBL10364539 | 0.82 | HTT (0.51) | HTTKMT2ANPC1RAB9AATM | |
| SCHEMBL10897041 | 0.81 | RXRA (0.50) | HTTKMT2AL3MBTL1NPC1RAB9A | |
| SCHEMBL2850399 | 0.81 | MAPT (0.74) | HTTKMT2ANPC1RAB9AATM | |
| SCHEMBL10340603 | 0.79 | HTT (0.78) | HTTKMT2ARAB9AALDH1A1MAPT | |
| SCHEMBL10365525 | 0.79 | HTT (0.54) | HTTKMT2ANPC1RAB9AATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0151866-B1 | HERBICIDAL PYRAZOLE-(THIO)-CARBOXAMIDES | ELI LILLY AND COMPANY (US) | 1990-07-25 | — | — | EP | disclosed |
| US-4620865-A | Herbicidal and algicidal 1,5-disubstituted-1H-pyrazole-4-carboxamides | ELI LILLY AND COMPANY (US) | 1986-11-04 | — | — | US | disclosed |
| EP-0151866-A2 | Herbicidal pyrazole-(thio)-carboxamides | ELI LILLY AND COMPANY (US) | 1985-08-21 | — | — | EP | disclosed |