Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 8/20 | 0.39 |
| ▸ | AR | P10275 | 2/20 | 0.38 |
| ▸ | MAP3K14 | Q99558 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.35 |
| ▸ | DPP4 | P27487 | 1/20 | 0.35 |
| ▸ | TRPM4 | Q8TD43 | 1/20 | 0.34 |
| ▸ | TRPM5 | Q9NZQ8 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10365101 | 0.85 | CYP19A1 (0.53) | CYP19A1ARMEN1KMT2A | |
| SCHEMBL10365621 | 0.84 | RET (0.42) | AR | |
| SCHEMBL10366584 | 0.83 | MAOB (0.41) | CYP19A1AR | |
| SCHEMBL10367118 | 0.81 | CYP19A1 (0.58) | CYP19A1ARMEN1KMT2ATDP1 | |
| SCHEMBL10365195 | 0.77 | KDM4E (0.46) | CYP19A1MEN1KMT2ATDP1DPP4 | |
| SCHEMBL10365193 | 0.76 | FUCA1 (0.40) | MEN1KMT2A | |
| SCHEMBL10365725 | 0.74 | GRIN2B (0.43) | MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL10365192 | 0.73 | ABCG2 (0.51) | CYP19A1ARMEN1KMT2ATDP1 | |
| SCHEMBL10574481 | 0.73 | MAOB (0.45) | CYP19A1 | |
| SCHEMBL9379992 | 0.73 | CYP19A1 (0.36) | CYP19A1ARMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0250265-B1 | 2-PHENYLBENZOXEPIN DERIVATIVE | SUNTORY LIMITED (JP) | 1990-09-05 | — | — | EP | disclosed |
| US-4845094-A | HYPOGLYCEMIC, ANTICOAGULANT | SUNTORY LIMITED (JP) | 1989-07-04 | — | — | US | disclosed |
| EP-0250265-A1 | 2-Phenylbenzoxepin derivative | SUNTORY LIMITED (JP) | 1987-12-23 | — | — | EP | disclosed |