Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 6/20 | 0.58 |
| ▸ | MAOB | P27338 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | ABCG2 | Q9UNQ0 | 2/20 | 0.48 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.48 |
| ▸ | AR | P10275 | 1/20 | 0.48 |
| ▸ | CFTR | P13569 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10365192 | 0.90 | ABCG2 (0.51) | CYP19A1MAOBMEN1KMT2ATDP1 | |
| SCHEMBL10367170 | 0.85 | MAOB (0.48) | CYP19A1MAOBMEN1KMT2ATDP1 | |
| SCHEMBL17708851 | 0.85 | CYP19A1 (0.63) | CYP19A1MAOBMEN1KMT2ATDP1 | |
| SCHEMBL10365195 | 0.84 | KDM4E (0.46) | CYP19A1MEN1KMT2ATDP1ABCG2 | |
| Hydrochloric Acid SCHEMBL17709161 | 0.84 | CYP19A1 (0.62) | CYP19A1MAOBMEN1KMT2ATDP1 | |
| SCHEMBL10365101 | 0.82 | CYP19A1 (0.53) | CYP19A1MAOBMEN1KMT2AAR | |
| SCHEMBL10364752 | 0.81 | CYP19A1 (0.39) | CYP19A1MEN1KMT2ATDP1AR | |
| SCHEMBL10366584 | 0.80 | MAOB (0.41) | CYP19A1MAOBARCFTRMAPT | |
| SCHEMBL13894328 | 0.78 | CYP19A1 (0.61) | CYP19A1MAOBMEN1KMT2ATDP1 | |
| SCHEMBL6864759 | 0.77 | CYP2C19 (0.49) | CYP19A1MAOBMEN1KMT2ATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0250265-B1 | 2-PHENYLBENZOXEPIN DERIVATIVE | SUNTORY LIMITED (JP) | 1990-09-05 | — | — | EP | disclosed |
| US-4845094-A | HYPOGLYCEMIC, ANTICOAGULANT | SUNTORY LIMITED (JP) | 1989-07-04 | — | — | US | disclosed |
| EP-0250265-A1 | 2-Phenylbenzoxepin derivative | SUNTORY LIMITED (JP) | 1987-12-23 | — | — | EP | disclosed |