Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 6/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 4/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10978037 | 0.94 | CYP19A1 (0.46) | CYP19A1CYP3A4THRBADRA2CLMNA | |
| Penconazole SCHEMBL29416459 | 0.90 | CYP19A1 (0.41) | CYP19A1CYP3A4THRBADRA2CLMNA | |
| Penconazole SCHEMBL30015079 | 0.90 | CYP19A1 (0.41) | CYP19A1CYP3A4THRBADRA2CLMNA | |
| Penconazole SCHEMBL24791 | 0.90 | CYP19A1 (0.41) | CYP19A1CYP3A4THRBADRA2CLMNA | |
| Penconazole SCHEMBL3003031 | 0.90 | CYP19A1 (0.41) | CYP19A1CYP3A4THRBADRA2CLMNA | |
| Penconazole SCHEMBL8050480 | 0.90 | CYP19A1 (0.41) | CYP19A1CYP3A4THRBADRA2CLMNA | |
| SCHEMBL9480900 | 0.87 | CYP3A4 (0.40) | CYP19A1CYP3A4THRBADRA2CLMNA | |
| SCHEMBL10833443 | 0.87 | CYP19A1 (0.41) | CYP19A1CYP3A4THRBADRA2CLMNA | |
| SCHEMBL19279644 | 0.87 | KMT2A (0.41) | CYP19A1CYP3A4THRBPOLBKDM4E | |
| SCHEMBL29364531 | 0.86 | ADRA2C (0.44) | CYP19A1CYP3A4ADRA2CLMNAPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0082340-B1 | MICROBICIDAL TRIAZOLYL-ETHYL-ETHERS | CIBA-GEIGY AG (CH) | 1990-01-03 | — | — | EP | claimed |
| US-4598085-A | Fungicidal 1-(2-aryl-2-R-ethyl)-1H-1,2,4-triazoles | JANSSEN PHARMACEUTICA N.V. (BE) | 1986-07-01 | — | — | US | claimed |
| US-4598085-A | Fungicidal 1-(2-aryl-2-R-ethyl)-1H-1,2,4-triazoles | JANSSEN PHARMACEUTICA N.V. (BE) | 1986-07-01 | — | — | US | disclosed |