Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.34 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.32 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | MMP8 | P22894 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL179502 | 0.69 | — | — | |
| SCHEMBL82538 | 0.68 | TAAR1 (0.43) | TAAR1HPGDRAB9AADORA2AADORA1 | |
| SCHEMBL10856191 | 0.68 | CES1 (0.38) | LMNACYP2D6HPGDRAB9ACYP2C9 | |
| SCHEMBL11091944 | 0.67 | KCNH2 (0.52) | TAAR1HPGDRAB9AALDH1A1 | |
| Water SCHEMBL10981448 | 0.67 | TAAR1 (0.42) | TAAR1HPGDRAB9AADORA2AADORA1 | |
| SCHEMBL10737606 | 0.67 | CYP2C19 (0.37) | SLC6A2CYP2D6HPGDTSHRCYP2C19 | |
| Fluoride SCHEMBL28059937 | 0.66 | TAAR1 (0.41) | TAAR1HPGDRAB9AADORA2AADORA1 | |
| Methane SCHEMBL28186549 | 0.66 | KCNH2 (0.50) | TAAR1HPGDRAB9ACYP2C19CYP1A2 | |
| Toluene SCHEMBL28296566 | 0.65 | LMNA (0.48) | LMNAHPGDTSHRRAB9AADORA2A | |
| SCHEMBL28358439 | 0.65 | SLC6A2 (0.61) | TAAR1SLC6A2LMNACYP2D6TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0314478-B1 | NOVEL IMIDAZOLE COMPOUNDS, PROCESS FOR PREPARATION THEREOF ANTIFUNGAL AGENT AND MILDEWPROOF AGENT | SHIKOKU CHEMICALS CORPORATION (JP) | 1990-09-05 | — | — | EP | disclosed |
| US-4912123-A | Imidazole compound | SHIKOKU CHEMICALS CORPORATION (JP) | 1990-03-27 | — | — | US | disclosed |
| EP-0314478-A1 | Novel imidazole compounds, process for preparation thereof antifungal agent and mildewproof agent | SHIKOKU CHEMICALS CORPORATION (JP) | 1989-05-03 | — | — | EP | disclosed |
| US-4720551-A | Chlorothienyl-imidazole propenones | SHIKOKU CHEMICALS CORPORATION (JP) | 1988-01-19 | — | — | US | disclosed |
| EP-0218398-A2 | Imidazole compound valuable as fungicidal agent and process for preparation thereof | SHIKOKU CHEMICALS CORPORATION (JP) | 1987-04-15 | — | — | EP | disclosed |