Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 2/20 | 0.43 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.43 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.43 |
| ▸ | NR1I2 | O75469 | 5/20 | 0.42 |
| ▸ | HTR2C | P28335 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 7/20 | 0.41 |
| ▸ | APEX1 | P27695 | 3/20 | 0.41 |
| ▸ | APAF1 | O14727 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | PLCG1 | P19174 | 1/20 | 0.41 |
| ▸ | ABCC2 | Q92887 | 1/20 | 0.41 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | PPARG | P37231 | 2/20 | 0.41 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.41 |
| ▸ | MMP2 | P08253 | 1/20 | 0.41 |
| ▸ | ALB | P02768 | 1/20 | 0.41 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10365137 | 1.00 | PTGS1 (0.43) | PTGS1ABCB11PDE4DNR1I2HTR2C | |
| SCHEMBL9364696 | 1.00 | PTGS1 (0.43) | PTGS1ABCB11PDE4DNR1I2HTR2C | |
| SCHEMBL9364702 | 1.00 | PTGS1 (0.43) | PTGS1ABCB11PDE4DNR1I2HTR2C | |
| SCHEMBL9623509 | 0.94 | PTGS1 (0.43) | PTGS1ABCB11PDE4DNR1I2HTR2C | |
| SCHEMBL9360945 | 0.94 | PTGS1 (0.43) | PTGS1ABCB11PDE4DNR1I2HTR2C | |
| SCHEMBL9360942 | 0.94 | PTGS1 (0.43) | PTGS1ABCB11PDE4DNR1I2HTR2C | |
| SCHEMBL9623505 | 0.94 | PTGS1 (0.43) | PTGS1ABCB11PDE4DNR1I2HTR2C | |
| SCHEMBL10367503 | 0.94 | PTGS1 (0.43) | PTGS1ABCB11PDE4DNR1I2HTR2C | |
| SCHEMBL10367505 | 0.94 | PTGS1 (0.43) | PTGS1ABCB11PDE4DNR1I2HTR2C | |
| SCHEMBL9196828 | 0.93 | PTGS1 (0.44) | PTGS1ABCB11PDE4DNR1I2HTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0121244-B1 | CEPHALOSPORIN DERIVATIVES | Bristol-Myers Company (US) | 1990-09-12 | — | — | EP | disclosed |
| US-4525473-A | BACTERICIDES | BRISTOL-MYERS COMPANY (US) | 1985-06-25 | — | — | US | disclosed |
| US-4507487-A | CHEMICAL INTERMEDIATES FOR CEPHALOSPORINS | BRISTOL-MYERS COMPANY (US) | 1985-03-26 | — | — | US | disclosed |
| US-4500526-A | ANTIBIOTICS, BACTERICIDES | BRISTOL-MYERS COMPANY (US) | 1985-02-19 | — | — | US | disclosed |
| US-4486586-A | BACTERICIDAL ANTIBIOTICS | BRISTOL-MYERS COMPANY (US) | 1984-12-04 | — | — | US | disclosed |
| EP-0121244-A2 | Cephalosporin derivatives | Bristol-Myers Company (US) | 1984-10-10 | — | — | EP | disclosed |