Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 2/20 | 0.44 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.44 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 7/20 | 0.44 |
| ▸ | APEX1 | P27695 | 3/20 | 0.44 |
| ▸ | APAF1 | O14727 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | PLCG1 | P19174 | 1/20 | 0.44 |
| ▸ | ABCC2 | Q92887 | 1/20 | 0.44 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.44 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.43 |
| ▸ | MMP2 | P08253 | 1/20 | 0.43 |
| ▸ | NR1I2 | O75469 | 6/20 | 0.43 |
| ▸ | HTR2C | P28335 | 1/20 | 0.43 |
| ▸ | PPARG | P37231 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | SLC22A6 | Q4U2R8 | 2/20 | 0.42 |
| ▸ | SLC22A8 | Q8TCC7 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10636340 | 1.00 | PTGS1 (0.44) | PTGS1ABCB11PDE4DTDP1APEX1 | |
| SCHEMBL5712680 | 0.95 | PTGS1 (0.43) | PTGS1ABCB11PDE4DTDP1APEX1 | |
| SCHEMBL5712682 | 0.95 | PTGS1 (0.43) | PTGS1ABCB11PDE4DTDP1APEX1 | |
| SCHEMBL9361240 | 0.94 | PTGS1 (0.44) | PTGS1ABCB11PDE4DTDP1APEX1 | |
| SCHEMBL9361234 | 0.94 | PTGS1 (0.44) | PTGS1ABCB11PDE4DTDP1APEX1 | |
| SCHEMBL9204591 | 0.94 | PTGS1 (0.45) | PTGS1ABCB11PDE4DTDP1APEX1 | |
| SCHEMBL9827358 | 0.94 | PTGS1 (0.45) | PTGS1ABCB11PDE4DTDP1APEX1 | |
| SCHEMBL9362001 | 0.93 | PTGS1 (0.45) | PTGS1ABCB11PDE4DTDP1APEX1 | |
| SCHEMBL9362010 | 0.93 | PTGS1 (0.45) | PTGS1ABCB11PDE4DTDP1APEX1 | |
| SCHEMBL10365136 | 0.93 | PTGS1 (0.43) | PTGS1ABCB11PDE4DTDP1APEX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0452987-B1 | Isoindoline derivatives | BANYU PHARMA CO LTD (JP) | 1995-03-01 | — | — | EP | disclosed |
| EP-0186187-B1 | CEPHALOSPORIN DERIVATIVES | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1992-02-26 | — | — | EP | disclosed |
| EP-0452987-A1 | Isoindoline derivatives | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1991-10-23 | — | — | EP | disclosed |
| EP-0182210-B1 | CEPHALOSPORIN DERIVATIVES | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1991-02-27 | — | — | EP | disclosed |
| US-4742053-A | ANTIBIOTICS | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1988-05-03 | — | — | US | disclosed |
| US-4677100-A | ANTIBIOTICS | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1987-06-30 | — | — | US | disclosed |
| EP-0186187-A2 | Cephalosporin derivatives | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1986-07-02 | — | — | EP | disclosed |
| EP-0182210-A2 | Cephalosporin derivatives | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1986-05-28 | — | — | EP | disclosed |