SCHEMBL10365232

SCHEMBL10365232

[CH2]CCNCCCNC(C)C

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2C19 P33261 2/20 0.36
MEN1 O00255 1/20 0.36
GLA P06280 1/20 0.36
KMT2A Q03164 1/20 0.36
CYP1A2 P05177 1/20 0.35
CA12 O43570 1/20 0.32
CA2 P00918 1/20 0.32
CA3 P07451 1/20 0.32
CA4 P22748 1/20 0.32
CA6 P23280 1/20 0.32
CA5A P35218 1/20 0.32
CA7 P43166 1/20 0.32
CA9 Q16790 1/20 0.32
CA14 Q9ULX7 1/20 0.32
CA5B Q9Y2D0 1/20 0.32
HRH4 Q9H3N8 2/20 0.31
HRH3 Q9Y5N1 2/20 0.31
ALDH1A1 P00352 1/20 0.31
TSHR P16473 1/20 0.31
ADRB2 P07550 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10365182 0.95 ALDH1A1 (0.36) CYP2C19MEN1GLAKMT2ACYP1A2
SCHEMBL10363816 0.93 HRH4 (0.36) CYP2C19CYP1A2HRH4HRH3ALDH1A1
SCHEMBL10365397 0.91 CYP2C19 (0.36) CYP2C19MEN1GLAKMT2ACYP1A2
SCHEMBL10363447 0.88 CYP2C19 (0.39) CYP2C19MEN1GLAKMT2ACYP1A2
SCHEMBL25565749 0.87 CYP2C19 (0.45) CYP2C19MEN1GLAKMT2ACYP1A2
SCHEMBL10365432 0.86 CYP2C19 (0.37) CYP2C19MEN1GLAKMT2ACYP1A2
SCHEMBL10365223 0.86 ALDH1A1 (0.36) CYP2C19MEN1GLAKMT2ACYP1A2
SCHEMBL10365240 0.86 ALDH1A1 (0.36) CYP2C19MEN1GLAKMT2ACYP1A2
SCHEMBL10364493 0.85
SCHEMBL12319688 0.85 CYP2C19 (0.48) CYP2C19MEN1GLAKMT2ACYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4918107-A HYDROXYPHENYLACETYL-L-ASPARAGINYL COMPOUNDS TSUMURA & CO. (JP) 1990-04-17 US disclosed